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  2. Folate deficiency - Wikipedia

    en.wikipedia.org/wiki/Folate_deficiency

    Folate deficiency, also known as vitamin B 9 deficiency, is a low level of folate and derivatives in the body. [1] This may result in megaloblastic anemia in which red blood cells become abnormally large, and folate deficiency anemia is the term given for this medical condition. [3] Signs of folate deficiency are often subtle. [4]

  3. Folate - Wikipedia

    en.wikipedia.org/wiki/Folate

    Veterinarians may test cats and dogs if a risk of folate deficiency is indicated. Cats with exocrine pancreatic insufficiency, more so than dogs, may have low serum folate. In dog breeds at risk for cleft lip and cleft palate dietary folic acid supplementation significantly decreased incidence. [150]

  4. Anemia - Wikipedia

    en.wikipedia.org/wiki/Anemia

    Deficiency in folate or vitamin B 12 can be due either to inadequate intake or insufficient absorption. Folate deficiency normally does not produce neurological symptoms, while B 12 deficiency does. Pernicious anemia is caused by a lack of intrinsic factor, which is required to absorb vitamin B 12 from food.

  5. Vitamin deficiency - Wikipedia

    en.wikipedia.org/wiki/Vitamin_deficiency

    Folate (Vitamin B 9) deficiency: Symptoms may include feeling tired, heart palpitations, shortness of breath, feeling faint, open sores on the tongue, loss of appetite, changes in the color of the skin or hair, irritability, and behavioral changes. [32] In adults, anemia (macrocytic, megaloblastic anemia) can be a sign of advanced folate ...

  6. FolateFolate deficiency is believed to be primary to the following secondary conditions: Megaloblastic anemia; Calcification of brain channels – epilepsy, dementia, visual manifestations. B 6 deficiency. Vitamin B 6 deficiency can result in neuropathies and increases in pain sensitivity.

  7. Dihydrofolate reductase deficiency - Wikipedia

    en.wikipedia.org/wiki/Dihydrofolate_reductase...

    Dihydrofolate reductase deficiency (DHFR deficiency) is a rare inherited disorder of folate metabolism caused by defects in the DHFR gene. The disorder is inherited in the autosomal recessive manner and may present with megaloblastic anemia, cerebral folate deficiency and neurological symptoms of varying type and severity. The patient may have ...

  8. Cerebral folate deficiency - Wikipedia

    en.wikipedia.org/wiki/Cerebral_folate_deficiency

    For people with the FOLR1 mutation, even when the systemic deficiency is corrected by folate, the cerebral deficiency remains and must be treated with folinic acid. Success depends on early initiation of treatment and treatment for a long period of time. [9] [3] Fewer than 20 people with the FOLR1 defect have been described in the medical ...

  9. Imerslund–Gräsbeck syndrome - Wikipedia

    en.wikipedia.org/wiki/Imerslund–Gräsbeck_syndrome

    In absence of vitamin B 12, levels of methylmalonyl CoA increase, and this is in fact a great way to distinguish folate deficiency macrocytic anemia, from vitamin B 12 deficiency anemia. The following is the reaction in which Ado B 12, plays a pivotal role: Propionyl CoA → Methylmalonyl CoA → Succinyl CoA [5]

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