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Norethisterone (3-ketolynestrenol), the active metabolite of lynestrenol.. Lynestrenol itself does not bind to the progesterone receptor and is inactive as a progestogen. [7] [8] It is a prodrug, and upon oral administration, is rapidly and almost completely converted into norethisterone, a potent progestogen, in the liver during first-pass metabolism.
After an intake of 1.5 mg levonorgestrel in clinical trials, very common side effects (reported by 10% or more) included: hives, dizziness, hair loss, headache, nausea, abdominal pain, uterine pain, delayed menstruation, heavy menstruation, uterine bleeding, and fatigue; common side effects (reported by 1% to 10%) included diarrhea, vomiting ...
You may even wonder how to delay your period so you can avoid the pesky side effects altogether. Sound familiar? If so, good news: It's possible to delay your period safely, doctors say.
Side effects of norethisterone include menstrual irregularities, headaches, nausea, breast tenderness, mood changes, acne, increased hair growth. [ 16 ] [ 17 ] Norethisterone is a progestin, or a synthetic progestogen , and hence is an agonist of the progesterone receptor , the biological target of progestogens like progesterone .
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Common side effects include menstrual disturbances such as absence of periods, abdominal pain, and headaches. [10] More serious side effects include bone loss, blood clots, allergic reactions, and liver problems. [10] Use is not recommended during pregnancy as it may harm the baby. [10]
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