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They have a 4.5-star average rating from 450 reviews on Amazon. ... azelaic acid and vitamin C all function as tyrosinase inhibitors, meaning that, as with kojic acid, they prevent the formation ...
This low-cost serum uses hyaluronic acid to fade hyperpigmentation, hydrate skin, reduce the appearance of fine lines and wrinkles and brighten your whole face. $10 at Amazon
Hyperpigmentation is believed to be related to the enzyme tyrosinase which produces melanin. Among several chemicals known to inhibit tyrosinase production, such as hydroquinone , arbutin , and kojic acid , 4-butylresorcinol has been found to be the most powerful inhibitor by a wide margin.
Several skin whitening agents, including tyrosinase inhibitors, have been found to cause an increase in the expression of tyrosinase, which by itself would increase melanin synthesis. [ 41 ] Microphthalmia-associated transcription factor (MITF) is the master transcription factor that controls the expression of TYR, TRP1, and TRP2, MART1 ...
And, while many of the best skin-tightening creams will cost you more than a night's stay in a 5-star resort, the truth is there are plenty of perfectly good lotions and potions on Amazon that ...
Tyrosinase is an enzyme needed in melanin synthesis in the melanin producing cell of the skin, the melanocyte. By reducing the activity of tyrosinase, β-arbutin reduces the synthesis of melanin, leading to a lighter skin tone and the diminished appearance of hyperpigmentation. It is not as potent an inhibitor of tyrosinase as α-arbutin. [6]
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