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  2. Allopurinol - Wikipedia

    en.wikipedia.org/wiki/Allopurinol

    Allopurinol is a medication used to decrease high blood uric acid levels. [5] It is specifically used to prevent gout, prevent specific types of kidney stones and for the high uric acid levels that can occur with chemotherapy. [6] [7] It is taken orally (by mouth) or intravenously (injected into a vein). [7]

  3. Your Gout Guide: From Symptoms to Treatment - AOL

    www.aol.com/gout-guide-symptoms-treatment...

    These can help prevent gout flares and further complications. According to the American College of Rheumatology guidelines, allopurinol is the first-line medication for lowering uric acid levels ...

  4. Gout - Wikipedia

    en.wikipedia.org/wiki/Gout

    Gout presenting as slight redness in the metatarsophalangeal joint of the big toe. Gout can present in several ways, although the most common is a recurrent attack of acute inflammatory arthritis (a red, tender, hot, swollen joint). [4] The metatarsophalangeal joint at the base of the big toe is affected most often, accounting for half of cases ...

  5. Xanthine oxidase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Xanthine_oxidase_inhibitor

    A xanthine oxidase inhibitor is any substance that inhibits the activity of xanthine oxidase, an enzyme involved in purine metabolism.In humans, inhibition of xanthine oxidase reduces the production of uric acid, and several medications that inhibit xanthine oxidase are indicated for treatment of hyperuricemia and related medical conditions including gout. [1]

  6. Tophus - Wikipedia

    en.wikipedia.org/wiki/Tophus

    When uric acid levels and gout symptoms cannot be controlled with standard gout medicines that decrease the production of uric acid (e.g., allopurinol, febuxostat) or increase uric acid elimination from the body through the kidneys (e.g., probenecid), this can be referred to as refractory chronic gout (RCG). [3]

  7. Lesinurad/allopurinol - Wikipedia

    en.wikipedia.org/wiki/Lesinurad/allopurinol

    Lesinurad/allopurinol (trade name Duzallo) is a fixed-dose combination drug for the treatment of gout. [1] It contains 200 mg of lesinurad and 300 mg of allopurinol.In August 2017, the US Food and Drug Administration approved it for the treatment of hyperuricemia associated with gout in patients for whom target serum uric acid levels have not been achieved with allopurinol alone. [2]

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