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In 1911, the anaesthetist Arthur Ernest Guedel first described the use of self-administration of a nitrous oxide and oxygen mix. It was not until 1961 that the first paper was published by Michael Tunstall and others, describing the administration of a pre-mixed 50:50 nitrous oxide and oxygen mix, which led to the commercialisation of the product.
The effect is named after Bernard Raymond Fink (1914–2000), whose 1955 paper first explained it. [1] [4] When a patient is recovering from N 2 O anaesthesia, large quantities of this gas cross from the blood into the alveoli (down its concentration gradient) and so for a short period of time, the O 2 and CO 2 in the alveoli are diluted by ...
The two general types of alternative pressure therapy are sham acupressure and the use of the P6 point. A 2015 study found no significant difference between the use of either therapy in the treatment or prevention of PONV. In a review of 59 studies, both therapies significantly affected the nausea aspect, but had no significant effect on vomiting.
Xenon is odorless (odourless) and rapid in onset, but is expensive and requires specialized equipment to administer and monitor. Nitrous oxide, even at 80% concentration, does not quite produce surgical level anaesthesia in most people at standard atmospheric pressure, so it must be used as an adjunct anaesthetic, along with other agents.
Nitrous oxide atmospheric concentration since 1978 Annual growth rate of atmospheric nitrous oxide since 2000 Earth's nitrous oxide budget from the Global Carbon Project (2020) [57] Nitrous oxide is a minor component of Earth's atmosphere and is an active part of the planetary nitrogen cycle .
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TIVA is used to induce general anesthesia while avoiding the disadvantages of volatile anesthesia (and traditional inhalation agents). [9] Intravenous anesthetic agents are titrated at safe doses to maintain stage III surgical anesthesia (unconsciousness, amnesia, immobility, and absence of response to noxious stimulation). [10]
"The Hydrating Effects of Hypertonic, Isotonic and Hypotonic Sports Drinks and Waters on Central Hydration During Continuous Exercise: A Systematic Meta-Analysis and Perspective." Sports Medicine ...
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