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Drug-induced fever is a symptom of an adverse drug reaction wherein the administration of drugs intended to help a patient causes a hypermetabolic state resulting in fever. The drug may interfere with heat dissipation peripherally, increase the rate of metabolism , evoke a cellular or humoral immune response , mimic endogenous pyrogen , or ...
In humans, hyperthermia is defined as a temperature greater than 37.5–38.3 °C (99.5–100.9 °F), depending on the reference used, that occurs without a change in the body's temperature set point. [3] [10] The normal human body temperature can be as high as 37.7 °C (99.9 °F) in the late afternoon. [2]
Hyperthermia is defined as supra-normal body temperatures. There is no consensus as to what is the safest or most effective target temperature for the whole body. During treatment the body temperature reaches a level between 39.5 and 40.5 °C (103.1 and 104.9 °F). [4]
Simplified control circuit of human thermoregulation. [8] The core temperature of a human is regulated and stabilized primarily by the hypothalamus, a region of the brain linking the endocrine system to the nervous system, [9] and more specifically by the anterior hypothalamic nucleus and the adjacent preoptic area regions of the hypothalamus ...
Heat illness is a spectrum of disorders due to increased body temperature. It can be caused by either environmental conditions or by exertion.It includes minor conditions such as heat cramps, heat syncope, and heat exhaustion as well as the more severe condition known as heat stroke. [1]
The ideal temperature for sleep is typically between 60°F and 67°F for most adults, says Martina Vendrame, M.D., neurologist and sleep medicine specialist at Lehigh Valley Health Network.
When heat comes from a direct contact source it has to heat the external layer of the skin, and heat is transferred to the deeper layer by conduction. Since heat conduction needs a temperature gradient to proceed, and there is a maximum temperature that can be safely used (around 42 °C), this means lower temperature where warming is needed.
The human body always works to remain in homeostasis. One form of homeostasis is thermoregulation. Body temperature varies in every individual, but the average internal temperature is 37.0 °C (98.6 °F). [1] Sufficient stress from extreme external temperature may cause injury or death if it exceeds the ability of the body to thermoregulate.