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Clotrimazole, sold under the brand name Lotrimin, among others, is an antifungal medication. [2] It is used to treat vaginal yeast infections, oral thrush, diaper rash, tinea versicolor, and types of ringworm including athlete's foot and jock itch. [2] It can be taken by mouth or applied as a cream to the skin or in the vagina. [2]
[1] [2] It is a combination of clotrimazole and betamethasone dipropionate. [1] It is applied to the skin. [1] Common side effects include paresthesia, rash, edema, and secondary infections. [1] In 2022, it was the 242nd most commonly prescribed medication in the United States, with more than 1 million prescriptions. [3] [4]
Antifungal resistance is a One Health concern, driven by multiple extrinsic factors, including extensive fungicidal use, overuse of clinical antifungals, environmental change and host factors. [1] Like resistance to antibacterials, antifungal resistance can be driven by antifungal use in agriculture.
Butenafine, sold under the brand names Lotrimin Ultra, Mentax, and Butop (In India only), is a synthetic benzylamine derived antifungal drug. It is structurally related to the allylamine antifungals terbinafine & naftifine .
Nystatin is also used to treat fungal infections in the vaginal area. It is commonly formulated into pessaries or vaginal cream for application. Ointments, gels, creams or dusting powder may be used when patients develop cutaneous lesions. Skin irritations may occur in some patients after applying the medication vaginally.
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