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Danuglipron is a small-molecule GLP-1 agonist developed by Pfizer [1] that, in an oral formulation, is under investigation as a therapy for diabetes mellitus. Initial results from a randomized controlled trial indicate that it reduced weight [2] and improved diabetic control. The most commonly reported adverse events were nausea, diarrhea, and ...
Pfizer announced on Dec. 1 that it was discontinuing phase 3 clinical trials of the twice-daily version due to high rates of adverse side effects. While these were mostly mild, a large percentage ...
2. Eat Smaller, More Frequent Meals. Instead of three main meals, try eating smaller, more frequent meals throughout the day. This can help if nausea is making it hard to feel like eating or if ...
Some claimed vaccine injuries are not, in fact, caused by vaccines; for example, there is a subculture of advocates who attribute their children's autism to vaccine injury, [7] despite the fact that vaccines do not cause autism. [8] [9] Claims of vaccine injuries appeared in litigation in the United States in the latter part of the 20th century.
In the original clinical trials for Pfizer-BioNTech's COVID-19 vaccine, for example, less than half of study participants reported side effects, but the shot worked well for the vast majority of ...
In the colon, bacteria will digest the complex carbohydrates, thereby causing gastrointestinal side effects such as flatulence and diarrhea. Since these effects are dose-related, it is generally advised to start with a low dose and gradually increase the dose to the desired amount. Pneumatosis cystoides intestinalis is another reported side ...
Berberine can upset your gastrointestinal system, causing symptoms like: nausea, diarrhea, constipation, gas and abdominal pain, Simmons says. It’s also possible that taking berberine can ...
Drugs used in diabetes treat diabetes mellitus by decreasing glucose levels in the blood. With the exception of insulin , most GLP-1 receptor agonists ( liraglutide , exenatide , and others), and pramlintide , all diabetes medications are administered orally and are thus called oral hypoglycemic agents or oral antihyperglycemic agents.