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Protein kinase B (PKB), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration.
The Akt signaling pathway or PI3K-Akt signaling pathway is a signal transduction pathway that promotes survival and growth in response to extracellular signals. Key proteins involved are PI3K (phosphatidylinositol 3-kinase) and Akt (protein kinase B).
RAC(Rho family)-alpha serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT1 gene.This enzyme belongs to the AKT subfamily of serine/threonine kinases that contain SH2 (Src homology 2-like) protein domains. [5]
As the name suggests, a non-nucleophilic base is a sterically hindered organic base that is a poor nucleophile.Normal bases are also nucleophiles, but often chemists seek the proton-removing ability of a base without any other functions.
Creatine (/ ˈ k r iː ə t iː n / or / ˈ k r iː ə t ɪ n /) [1] is an organic compound with the nominal formula (H 2 N)(HN)CN(CH 3)CH 2 CO 2 H.It exists in various tautomers in solutions (among which are neutral form and various zwitterionic forms).
In general, as temperature decreases from 25 °C to 5 °C the pH of a tris buffer will increase an average of 0.03 units per degree. As temperature rises from 25 °C to 37 °C, the pH of a tris buffer will decrease an average of 0.025 units per degree.
In inorganic chemistry, bicarbonate (IUPAC-recommended nomenclature: hydrogencarbonate [2]) is an intermediate form in the deprotonation of carbonic acid. It is a polyatomic anion with the chemical formula H C O − 3. Bicarbonate serves a crucial biochemical role in the physiological pH buffering system. [3]
γ-Butyrolactone (GBL) or gamma-butyrolactone is an organic compound with the formula O=CO(CH 2) 3.It is a hygroscopic, colorless, water-miscible liquid with a weak characteristic odor.