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Neuromyelitis optica (NMO) is a particular disease within the NMOSD spectrum. It is characterised by optic neuritis and longitudinally extensive myelitis. In more than 80% of NMO cases, the cause is immunoglobulin G autoantibodies to aquaporin 4 , the most abundant water channel protein in the central nervous system. [5] [1] [4]
Seropositive Devic's disease, according to the diagnostic criteria described above. Limited forms of Devic's disease, such as single or recurrent events of longitudinally extensive myelitis, and bilateral simultaneous or recurrent optic neuritis. Asian optic-spinal MS - this variant can present brain lesions like MS. [18]
Neuromyelitis optica, or Devic's disease; Idiopathic inflammatory demyelinating diseases; Leukodystrophic or dysmyelinating disorders: CNS neuropathies such as those produced by vitamin B 12 deficiency; Central pontine myelinolysis; Myelopathies such as tabes dorsalis (syphilitic myelopathy) Leukoencephalopathies such as progressive multifocal ...
The meaning of this fact is controversial. For some investigation teams it means that MS is a heterogeneous disease. Others maintain that the shape of the scars can change with time from one type to other and this could be a marker of the disease evolution. [63] Anyway, the heterogeneity could be true only for the early stage of the disease. [64]
Neuromyelitis optica or Devic's disease: immune attack on optic nerve and spinal cord; Sjögren's syndrome: destruction of the exocrine system of the body; Systemic lupus erythematosus: a systemic autoimmune disease featuring a wide variety of neurological signs and symptoms; Sarcoidosis: [4] chronic inflammatory cells form as nodules in ...
Pre-existing medical conditions, such as benign paroxysmal positional vertigo (BPPV) and Parkinson’s disease, can make you more susceptible to motion sickness, according to Cleveland Clinic.
The 24-hour flu is usually a type of gastroenteritis, which is an inflammation of the intestines and stomach, says William Schaffner, M.D., an infectious disease specialist and professor at the ...
Anti-AQP4 diseases, are a group of diseases characterized by auto-antibodies against aquaporin 4.. After the discovery of anti-AQP4 autoantibody in neuromyelitis optica, it was found that it was also present in some patients with other clinically defined diseases, including multiple sclerosis variants like optic-spinal MS.