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  2. Penicillin - Wikipedia

    en.wikipedia.org/wiki/Penicillin

    For this reason Gram-positive bacteria are very susceptible to penicillin (as first evidenced by the discovery of penicillin in 1928 [46]). [47] Penicillin, or any other molecule, enters Gram-negative bacteria in a different manner. The bacteria have thinner cell walls but the external surface is coated with an additional cell membrane, called ...

  3. Infection - Wikipedia

    en.wikipedia.org/wiki/Infection

    Antibiotics only work for bacteria and do not affect viruses. Antibiotics work by slowing down the multiplication of bacteria or killing the bacteria. The most common classes of antibiotics used in medicine include penicillin , cephalosporins , aminoglycosides , macrolides , quinolones and tetracyclines .

  4. Antimicrobial spectrum - Wikipedia

    en.wikipedia.org/wiki/Antimicrobial_spectrum

    Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.

  5. Bactericide - Wikipedia

    en.wikipedia.org/wiki/Bactericide

    Bactericidal antibiotics kill bacteria; bacteriostatic antibiotics slow their growth or reproduction. Bactericidal antibiotics that inhibit cell wall synthesis: the beta-lactam antibiotics ( penicillin derivatives ( penams ), cephalosporins ( cephems ), monobactams , and carbapenems ) and vancomycin .

  6. List of infectious diseases - Wikipedia

    en.wikipedia.org/wiki/List_of_infectious_diseases

    multiple bacteria Bacterial meningitis: Lumbar puncture (contraindicated if there is a mass in the brain or the intracranial pressure is elevated), CT or MRI Antibiotics No multiple bacteria Bacterial pneumonia: Sputum Gram stain and culture, Chest radiography Antibiotics No List of bacterial vaginosis microbiota: Bacterial vaginosis

  7. Penicillium - Wikipedia

    en.wikipedia.org/wiki/Penicillium

    Some members of the genus produce penicillin, a molecule that is used as an antibiotic, which kills or stops the growth of certain kinds of bacteria. Other species are used in cheesemaking . According to the Dictionary of the Fungi (10th edition, 2008), the widespread genus contains over 300 species.

  8. History of penicillin - Wikipedia

    en.wikipedia.org/wiki/History_of_penicillin

    Glass phial of British Standard penicillin. The history of penicillin follows observations and discoveries of evidence of antibiotic activity of the mould Penicillium that led to the development of penicillins that became the first widely used antibiotics. Following the production of a relatively pure compound in 1942, penicillin was the first ...

  9. Antimicrobial peptides - Wikipedia

    en.wikipedia.org/wiki/Antimicrobial_peptides

    Antimicrobial peptides have been demonstrated to kill Gram negative and Gram positive bacteria, [1] enveloped viruses, fungi and even transformed or cancerous cells. [2] Unlike the majority of conventional antibiotics it appears that antimicrobial peptides frequently destabilize biological membranes , can form transmembrane channels , and may ...