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Surgery is the main treatment, often combined with antibiotics. The prognosis is generally favorable, with minimal risk of lasting disability or recurrence. Brodie abscess is responsible for 2.5%-42% of primary bone infections. It is named after Sir Benjamin Collins Brodie, 1st Baronet, who initially described the condition in the 1830s.
Osteomyelitis; Other names: Bone infection: Osteomyelitis of the 1st toe: Specialty: Infectious disease, orthopedics: Symptoms: Pain in a specific bone, overlying redness, fever, weakness [1] Complications: Amputation [2] Usual onset: Young or old [1] Duration: Short or long term [2] Causes: Bacterial, fungal [2] Risk factors
Ceftriaxone, sold under the brand name Rocephin, is a third-generation cephalosporin antibiotic used for the treatment of a number of bacterial infections. [4] These include middle ear infections, endocarditis, meningitis, pneumonia, bone and joint infections, intra-abdominal infections, skin infections, urinary tract infections, gonorrhea, and pelvic inflammatory disease. [4]
Initial treatment typically includes antibiotics such as vancomycin, ceftriaxone or ceftazidime. [2] Surgery in the form of joint drainage is the gold standard management in large joints like the hip and shoulder. [2] [5] [8] Without early treatment, long-term joint problems may occur, such as irreversible joint destruction and dislocation. [2]
Vertebral osteomyelitis is a type of osteomyelitis (infection and inflammation of the bone and bone marrow) that affects the vertebrae. It is a rare bone infection concentrated in the vertebral column. [2] Cases of vertebral osteomyelitis are so rare that they constitute only 2%-4% of all bone infections. [3]
Antibiotics are used to treat cases involving infections. Penicillin is the first line of choice, although if this is contraindicated commonly used antimicrobials are: clindamycin, fluoroquinolones and/or metronidazole. Intravenous antibiotics may be used if the infection resists oral treatment.
According to a 2008 study, the incidence of discitis in the United States is around 0.4 to 2.4 per 100,000 people each year depending on age group. [5] According to a later 2016 study, the combined prevalence of discitis and vertebral osteomyelitis with or without spinal epidural abscess for persons under 20 years old is uncommon (0.3 per 100,000 persons), and higher in older patients (6.5 per ...
It may be used in combination with other antibiotics to treat pneumonia and can be used to prevent infection before surgery, particularly heart, lung, or bone surgery. [6] [14] When used to treat endocarditis, in combination with other antibiotics or alone, the dose of flucloxacillin may need to exceed the usual dose.
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