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Tolvaptan, sold under the brand name Samsca among others, is an aquaretic drug that functions as a selective, competitive vasopressin receptor 2 (V 2) antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
It is a prodrug of tolvaptan, [1] [2] formulated as the salt tolvaptan sodium phosphate, for intravenous administration. Tolvaptan phosphate is converted into the active drug tolvaptan in the human body following administration. It was developed by Otsuka Pharmaceutical Co. and was approved for use in Japan in 2022. [3]
24 News (Twenty Four News) is a free-to-air Indian Malayalam language news channel owned by Insight Media City. It was initially launched as a pilot in 2016 and officially began operations on December 8, 2018. The channel is headquartered in Kochi and has studios in Thiruvananthapuram and Kochi.
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The Miami Dolphins could be without their starting quarterback in a second straight must-win game.. Tua Tagovailoa's status for the Dolphins' Week 18 game against the New York Jets is "firmly in ...
The Bahamas has “firmly rejected” President-election Donald Trump's proposal to fly deported immigrants out of the U.S. and into the small island nation about 100 miles southeast of Florida ...
Hoda Kotb is reflecting on the moment a former boss body shamed her.. On the Dec. 2 episode of Today with Hoda & Jenna, the 60-year-old discussed Timothée Chalamet’s starring role in the ...
24 News: 2018 Insight Media City 2 Asianet News: 2001 FTA No Jupiter Entertainment Ventures: 3 Kairali News 2005 Kairali TV Network: 4 Manorama News: 2006 Malayala Manorama 5 JaiHind TV: 2007 Bharath Broadcasting Network 6 Raj News Malayalam 2011 Raj Television Network: 7 Reporter TV: 2011, Revamped on 1 July 2023