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Orthostatic hypotension can be a side effect of certain antidepressants, such as tricyclics [23] or monoamine oxidase inhibitors (MAOIs) [24] Alcohol can potentiate orthostatic hypotension to the point of syncope. [25] Orthostatic hypotension can also be a side effect of alpha-1 blockers (alpha 1 adrenergic blocking agents).
Orthostatic hypotension and syncope are associated with the body's poor ability to control blood pressure without active α-adrenergic receptors. The nasal congestion is exacerbated by changing body positions, because α 1 -adrenergic receptors also control nasal vascular blood flow and alpha blockers inhibit this, in the same way that alpha ...
Orthostatic syncope refers to syncope resulting from a postural decrease in blood pressure, termed orthostatic hypotension. [1]Orthostatic hypotension occurs when there is a persistent reduction in blood pressure of at least 20mmHg systolic or 10mmHg diastolic within three minutes of standing or being upright to 60 degrees on the head-up tilt table.
Orthostatic intolerance (OI) is the development of symptoms when standing upright that are relieved when reclining. [1] There are many types of orthostatic intolerance. OI can be a subcategory of dysautonomia , a disorder of the autonomic nervous system [ 2 ] occurring when an individual stands up. [ 3 ]
Three double-blind studies reported trazodone had antidepressant efficacy similar to that of other antidepressants in geriatric patients. Unfortunately, a side effect of trazodone, orthostatic hypotension, which may cause dizziness and increase the risk of falling, can have devastating consequences for elderly patients. [28]
Fluoxetine (Prozac) was similar to sertraline when it came to this side effect. Researchers also estimated that escitalopram, paroxetine, and duloxetine each had an associated 10-15% higher risk ...
This postural hypotension usually happens shortly after the first dose is absorbed into the blood and can result in syncope (fainting). Syncope occurs in approximately 1% of patients given an initial dose of 2 mg prazosin or greater. This adverse effect is self-limiting and in most cases does not recur after the initial period of therapy or ...
Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [2] It is used for the treatment of major depressive disorder, obsessive–compulsive disorder (OCD), anxiety, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. [2]