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Cortisone is a pregnene (21-carbon) steroid hormone. It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug. Cortisol is converted by the action of the enzyme corticosteroid 11-beta-dehydrogenase isozyme 2 into the inactive metabolite cortisone, particularly in the kidneys.
Mometasone, also known as mometasone y 3 s, is a steroid (specifically, a glucocorticoid) medication used to treat certain skin conditions, hay fever, and asthma. [10] [11] [12] Specifically it is used to prevent rather than treat asthma attacks. [10] It can be applied to the skin, inhaled, or used in the nose.
Pimobendan (INN, or pimobendane), sold under the brand name Vetmedin among others, is a veterinary medication. It is a calcium sensitizer and a selective inhibitor of phosphodiesterase 3 (PDE3) with positive inotropic and vasodilator effects. Pimobendan is used in the management of heart failure in dogs, most commonly caused by myxomatous ...
Pages in category "Prodrugs" The following 200 pages are in this category, out of approximately 285 total. ... Cortisone; Cortisone acetate; Cortobenzolone; CRL ...
Lewis Sarett of Merck & Co. was the first to synthesize cortisone, using a 36-step process that started with deoxycholic acid, which was extracted from ox bile. [56] The low efficiency of converting deoxycholic acid into cortisone led to a cost of US$200 per gram in 1947.
Kuranda Chew-Proof Elevated Dog Bed $58.95 at Walmart. Kuranda Chew-Proof Elevated Dog Bed $80.95 at Kuranda USA. Kuranda’s elevated dog beds are a favorite among our experts. “I adore the ...
White dog shaker syndrome (also known as idiopathic steroid responsive shaker syndrome, shaker dog syndrome and "little white shakers" syndrome; Latin name Idiopathic Cerebellitis) causes full body tremors in small dog breeds. It is most common in West Highland White Terriers, Maltese, Bichons, Poodles, [1] and other small dogs. There is a ...
A prodrug is a pharmacologically inactive medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologically active drug. [1][2] Instead of administering a drug directly, a corresponding prodrug can be used to improve how the drug is absorbed, distributed, metabolized, and excreted (ADME). [3][4]