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  2. Gene-centered view of evolution - Wikipedia

    en.wikipedia.org/wiki/Gene-centered_view_of...

    The gene-centered view of evolution, gene's eye view, gene selection theory, or selfish gene theory holds that adaptive evolution occurs through the differential survival of competing genes, increasing the allele frequency of those alleles whose phenotypic trait effects successfully promote their own propagation.

  3. DLX gene family - Wikipedia

    en.wikipedia.org/wiki/DLX_gene_family

    DLX genes are involved in craniofacial morphogenesis [9] [10] and the tangential migration of interneurons from the subpallium to the pallium during vertebrate brain development. [11] It has been suggested that DLX promotes the migration of interneurons by repressing a set of proteins that are normally expressed in terminally differentiated ...

  4. Pan-genome - Wikipedia

    en.wikipedia.org/wiki/Pan-genome

    The term 'pangenome' was defined with its current meaning by Tettelin et al. in 2005; [2] it derives 'pan' from the Greek word παν, meaning 'whole' or 'everything', while the genome is a commonly used term to describe an organism's complete genetic material.

  5. Regulator gene - Wikipedia

    en.wikipedia.org/wiki/Regulator_gene

    In genetics, a regulator gene, regulator, or regulatory gene is a gene involved in controlling the expression of one or more other genes. Regulatory sequences, which encode regulatory genes, are often at the five prime end (5') to the start site of transcription of the gene they regulate. In addition, these sequences can also be found at the ...

  6. Regulatory sequence - Wikipedia

    en.wikipedia.org/wiki/Regulatory_sequence

    Cis-regulatory DNA sequences that are located in DNA regions distant from the promoters of genes can have very large effects on gene expression, with some genes undergoing up to 100-fold increased expression due to such a cis-regulatory sequence. [3] These cis-regulatory sequences include enhancers, silencers, insulators and tethering elements. [4]

  7. Selfish genetic element - Wikipedia

    en.wikipedia.org/wiki/Selfish_genetic_element

    Selfish genetic elements (historically also referred to as selfish genes, ultra-selfish genes, selfish DNA, parasitic DNA and genomic outlaws) are genetic segments that can enhance their own transmission at the expense of other genes in the genome, even if this has no positive or a net negative effect on organismal fitness.

  8. Nested gene - Wikipedia

    en.wikipedia.org/wiki/Nested_gene

    Genes nested opposite the coding sequences of their host genes are very rare, and have been observed in prokaryotes, and more recently, in yeast (S. cerevisiae) and in Tetrahymena thermophila. These non-intronic nested genes remain to be identified in metazoan genomes. As with intronic nested genes, nonintronic nested genes typically do not ...

  9. Human genetics - Wikipedia

    en.wikipedia.org/wiki/Human_genetics

    The human genome is the total collection of genes in a human being contained in the human chromosome, composed of over three billion nucleotides. [2] In April 2003, the Human Genome Project was able to sequence all the DNA in the human genome, and to discover that the human genome was composed of around 20,000 protein coding genes.