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Antidepressant discontinuation syndrome, also called antidepressant withdrawal syndrome, is a condition that can occur following the interruption, reduction, or discontinuation of antidepressant medication following its continuous use of at least a month. [5]
This technique may be used if your medication puts you at risk for withdrawal symptoms, which may occur when some antidepressants are stopped without a gradual taper. Taper and moderate switch.
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The withdrawal symptoms for sertraline are less severe and frequent than for paroxetine, and more frequent than for fluoxetine. [86] [87] In most cases symptoms are mild, short-lived, and resolve without treatment. More severe cases are often successfully treated by temporary reintroduction of the drug with a slower tapering-off rate. [88]
It is considered a distinct phenomenon from antidepressant discontinuation syndrome, post-acute withdrawal syndrome, and major depressive disorder, [70] [68] and should be distinguished from sexual dysfunction associated with depression [70] and persistent genital arousal disorder. [64]
Zoloft is prescribed at several dosages, from 25mg to 200mg per day. Some side effects, including intimate effects, may be more common when Zoloft is used at a high dosage. Switching to a ...
Symptoms typically persist for a longer time frame in patients taking drugs which have a long elimination half-life, active metabolites, or a protracted duration of action. [ 6 ] Cases have reported persisting chronic symptoms, [ 75 ] and antidepressant discontinuation may contribute to ongoing features. [ 76 ]
However, there are differences between TCA related antidepressants and classical TCAs in terms of side effect profiles and withdrawal when compared to SSRIs. [67] There is evidence a prominent side-effect of antidepressants, emotional blunting, is confused with a symptom of depression itself. The cited study, according to Professor Linda Gask was: