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Guaifenesin might act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi via stimulation of the gastric mucosa. . This stimulation leads to an increased parasympathetic activity in the respiratory tract via the so-called gastro-pulmonary reflex, although some in vitro studies suggested that it might also act directly on the ...
A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract. The active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed effectiveness ).
Phenylpropanolamine (PPA), sold under many brand names, is a sympathomimetic agent which is used as a decongestant and appetite suppressant. [9] [1] [10] [11] It was previously commonly used in prescription and over-the-counter cough and cold preparations. The medication is taken by mouth. [4] [12]
Decongestants and expectorants are both effective at treating different cold and allergy symptoms. Decongestants are a type of medicine that can provide short-term relief for a blocked or stuffy ...
After an FDA advisory committee said the decongestant phenylephrine, an ingredient found in many oral cold and flu medications, is ineffective, experts weigh in on alternatives.
They provide temporary relief from symptoms of nasal congestion. Decongestants are available in oral and intranasal forms. Naphazoline and oxymetazoline are common topical (intranasal) decongestants, whilst pseudoephedrine is the most common example of oral decongestant used to reduce nasal congestion. Topical decongestants have a faster onset ...
The stakes are high, experts say, because a committee vote declaring phenylephrine ineffective as an oral decongestant could push the FDA to revoke the drug’s over-the-counter designation as ...
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
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