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Aciclovir, also known as acyclovir, [4] is an antiviral medication. [5] It is primarily used for the treatment of herpes simplex virus infections, chickenpox , and shingles . [ 6 ] Other uses include, prevention of cytomegalovirus infections following transplant, and severe complications of Epstein–Barr virus infection.
Aciclovir ophthalmic ointment and Trifluridine eye drops have similar effectiveness but are more effective than Idoxuridine and Vidarabine eye drops. [9] Oral acyclovir is as effective as topical antivirals for treating epithelial keratitis, and it has the advantage of no eye surface toxicity.
Idoxuridine is available as either a 0.5% ophthalmic ointment or as a 0.1% ophthalmic solution. [3] The dosage of the ointment is every 4 hours during day and once before bedtime. [ 3 ] The dosage of the solution is 1 drop in the conjunctival sac hourly during the day and every 2 hours during the night until definitive improvement, then 1 drop ...
Treatment: There are several antiviral medications to treat shingles, including acyclovir, valacyclovir, and famciclovir, per the CDC. Cool compresses, oatmeal baths, and calamine lotion may also ...
Antiviral Medications: Antiviral drugs such as acyclovir may be prescribed for viral folliculitis. Topical Antibiotics: Prescription-strength antibiotics like clindamycin or erythromycin.
Use Manufacturer Component Type Year approved Abacavir: HIV: ViiV Healthcare: Nucleoside analogue reverse transcriptase inhibitor (NRTI) 1998 Acyclovir (Aciclovir) Herpes Simplex, chickenpox, [2] varicella zoster virus: GSK: guanosine analogue RTI 1981 Adefovir: Hepatitis B [3] Gilead Sciences RTI 2002 , 2003 Amantadine: Influenza
However, topical ointment with acyclovir is discouraged since it offers minimal clinical benefits. Valacyclovir is a prodrug that is converted to acyclovir once in the body. It helps relieve the pain and discomfort and speeds healing of sores. It only comes in caplets and its advantage is that it has a longer duration of action than acyclovir. [21]
The most commonly used is acyclovir. Nucleotide and nucleoside analogues can also be found naturally. Examples include ddhCTP (3ʹ-deoxy-3′,4ʹdidehydro-CTP) produced by the human antiviral protein viperin [ 2 ] and sinefungin (a S-Adenosyl methionine analogue) produced by some Streptomyces .
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