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Cervical intraepithelial neoplasia (CIN), also known as cervical dysplasia, is the abnormal growth of cells on the surface of the cervix that could potentially lead to cervical cancer. [1] More specifically, CIN refers to the potentially precancerous transformation of cells of the cervix.
The loop electrosurgical excision procedure (LEEP) is one of the most commonly used approaches to treat high grade cervical dysplasia (CIN II/III, HGSIL) and early stage cervical cancer discovered on colposcopic examination. In the UK, it is known as large loop excision of the transformation zone (LLETZ).
Results from a phase 3 clinical trial show promise for a new standard of care for treating people with advanced cervical cancer. The new treatment includes a combination of induction chemotherapy ...
Cervical cancer staging is the ... to create the best treatment plan. [13] Cervical cancer is a type of ... 2 and 3, also known as high-grade SIL, indicate that more ...
LEEP cone biopsy displaying normal cervical epithelium (far left) progressing to borderline koilocytosis, to LSIL, and to HSIL (far right). A squamous intraepithelial lesion (SIL) is an abnormal growth of epithelial cells on the surface of the cervix, commonly called squamous cells.
This disease can progress to invasive cancer (squamous cell carcinoma) of the cervix. Cervical squamous intraepithelial lesion (SIL), previously called cervical intraepithelial neoplasia (CIN), is a form of dysplasia that can progress to cervical cancer. The term carcinoma in situ may be used interchangeably with high-grade SIL. [8]
[2] [3] [4] In the cervix, it is a rare, but very aggressive form of cervical cancer. In its early stages, neuroendocrine carcinoma is asymptomatic (not showing or producing indications of a disease or other medical condition).
Ratings of cervical intraepithelial neoplasia are also commonly used to grade cytology of cervical epithelium. Cervical intraepithelial neoplasia 1 is the most moderate and are low-grade squamous intraepithelial lesions while cervical intraepithelial neoplasia 2 and 3 are moderate to severe and are high-grade squamous intraepithelial lesions. [14]