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One of Pavlov’s dogs with a saliva-catch container and tube surgically implanted in its muzzle, Pavlov Museum, 2005. The history of animal testing goes back to the writings of the Ancient Greeks in the 4th and 3rd centuries BCE, with Aristotle (384–322 BCE) and Erasistratus (304–258 BCE) one of the first documented to perform experiments on nonhuman animals. [1]
Animal testing is widely used to aid in research of human disease when human experimentation would be unfeasible or unethical. [26] This strategy is made possible by the common descent of all living organisms, and the conservation of metabolic and developmental pathways and genetic material over the course of evolution. [27]
In 1954, the Universities Federation for Animal Welfare (UFAW) decided to sponsor systematic research on the progress of humane techniques in the laboratory. [2] In October of that year, William Russell, described as a brilliant young zoologist who happened to be also a psychologist and a classical scholar, and Rex Burch, a microbiologist, were appointed to inaugurate a systematic study of ...
Concern for animal welfare resurges in the 1950s, resulting in the federal Humane Slaughter Act [10] and the Animal Welfare Act. [11] 1966-2016: Intensive animal agriculture continues to grow, with the number of land animals slaughtered for food in the U.S. growing from 2.4 billion in 1965 to 9.2 billion in 2015. [12]
Rodents have been employed in biomedical experimentation from the 1650s. [1] Rodent studies up to the early 19th century were mainly physiological or toxicological.The first rodent behavioral study was carried out in 1822, a purely observational study [2], while quantitative rodent behavioral testing began in the late 19th century [1] [2].
Pages in category "History of animal testing" The following 5 pages are in this category, out of 5 total. This list may not reflect recent changes. ...
Between 90% and 95% of drugs that pass animal testing fail in human trials, which can take up to 15 years and cost between $1 billion and $6 billion, according to a news release from the Animal ...
Years later, animal testing ceased and instead an instrumented dummy was created as a replacement. In 1978, animals were their only subjects that could be a reliable substitution for the human being. The disadvantage, though, to using an instrumented dummy or a human cadaver, is that the tissue is not alive and will not elicit the same response ...