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Serious side effects may include abuse, but do not include pulmonary hypertension or valvular heart disease, as the latter complications were caused by the fenfluramine component of the "fen-phen" combination. [3] Phentermine is an norepinephrine and dopamine releasing agent (NDRA) and produces stimulant, rewarding, and appetite suppressant ...
Common side effects include tingling, dizziness, trouble sleeping, and constipation. [3] Serious side effects may include suicide, abuse. [3] Use is not recommended during pregnancy. [1] Phentermine is a stimulant and appetite suppressant. [3] Topiramate is an anticonvulsant that has weight loss side effects. [3]
Adverse effects were less frequent with the combination regimen than with the other active (non-placebo) treatments. The authors felt that combining fenfluramine and phentermine capitalized on their pharmacodynamic differences, resulting in equivalent weight loss, fewer adverse effects, and better appetite control. [4]
You may experience side effects like dizziness, mood changes, trouble sleeping, and headaches. Phentermine-topiramate. This is a combination of an appetite suppressant called phentermine and an ...
Also, currently available antidepressants all elicit undesirable side-effects, and new agents should be divested of the distressing side-effects of both first and second-generation antidepressants. [6] Another serious drawback of all antidepressants is the requirement for long-term administration prior to maximal therapeutic efficacy.
A 2005 meta-analysis of drug company data found no evidence that SSRIs increased the risk of suicide; however, important protective or hazardous effects could not be excluded. [ 134 ] A 2005 review observed that suicide attempts are increased in those who use SSRIs as compared to placebo and compared to therapeutic interventions other than ...
Avoid activities requiring mental alertness and coordination until drug effects are realized. Topiramate may impair heat regulation, [36] especially in children. Use caution with activities leading to an increased core temperature, such as strenuous exercise, exposure to extreme heat, or dehydration. Topiramate may cause visual field defects. [37]
The most common side effects of these drugs that led to withdrawals were mental disturbances, cardiac side effects, and drug abuse or drug dependence. Deaths were associated with seven products. [84] Ephedra was removed from the US market in 2004 over concerns that it raises blood pressure and could lead to strokes and death. [85]
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