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Tocolytics are used in preterm labor, which refers to when a baby is born too early before 37 weeks of pregnancy. As preterm birth represents one of the leading causes of neonatal morbidity and mortality, the goal is to prevent neonatal morbidity and mortality through delaying delivery and increasing gestational age by gaining more time for other management strategies like corticosteroids ...
Administration of tocolytic treatment with β2-adrenergic drugs has shown to stabilize uterine contractions while also effectively lowering Fetal Heart Rate. The usage of a balloon catheter to induce labor rather than Prostoglandin E 2 lowers the risk of uterine hyperstimulation and its effect on fetal heart rate.
Uterine Tachysystole is a condition of excessively frequent uterine contractions during pregnancy. [1] It is most often seen in induced or augmented labor, though it can also occur during spontaneous labor, [2] and this may result in fetal hypoxia and acidosis.
Similar to oxytocin, analogues bind to oxytocin receptors found along the muscles of the uterus and act as an agonist. During pregnancy, the number of oxytocin receptors increase until reaching their peak near completion of the pregnancy. An important note is that not all analogs of oxytocin work as an receptor agonist or as a uterotonic.
Atosiban is used to delay birth in adult women who are 24 to 33 weeks pregnant, when they show signs that they may give birth pre-term (prematurely). [4] These signs include regular contractions lasting at least 30 seconds at a rate of at least four every 30 minutes, [4] and dilation of the cervix (the neck of the womb) of 1 to 3 cm and an effacement (a measure of the thinness of the cervix ...
The exact cause of morning sickness remains unknown. Nausea and vomiting in pregnancy is typically mild and self-limited, resolving on its own by the 14th week of pregnancy. Other causes should also be ruled out when considering treatment. Initial treatment is typically conservative, and may include changes to diet and emotional support.
Isoxsuprine is used in humans for treatment of premature labor, i.e. a tocolytic, [6] and as a vasodilator for the treatment of cerebral vascular insufficiency, Raynaud's phenomenon, and other conditions. [7] Isoxsuprine may increase the heart rate, cause changes in blood pressure, and irritate the GI tract.
Suspected based on symptoms and examination, supported by testing the fluid or ultrasound [2] Differential diagnosis: Urinary incontinence, bacterial vaginosis [3] Treatment: Based on how far along a woman is in pregnancy and whether complications are present [2] Frequency ~8% of term pregnancies, [2] ~30% of preterm pregnancies [4]