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  2. Virtual Physiological Rat - Wikipedia

    en.wikipedia.org/wiki/Virtual_Physiological_Rat

    Computer simulation is used to integrate disparate data (genomic, anatomic, physiological, etc.) to explain and predict function, [4] and to translate the findings from animal models to yield new information on specific interrelated complex diseases in humans, including hypertension, kidney disease, heart failure, and metabolic syndrome. [5]

  3. Spontaneously hypertensive rat - Wikipedia

    en.wikipedia.org/wiki/Spontaneously_hypertensive_rat

    Spontaneously hypertensive rat (SHR) is a laboratory rat which is an animal model of primary hypertension, used to study cardiovascular disease. It is the most studied model of hypertension measured as number of publications. [ 1 ]

  4. Individually ventilated cage - Wikipedia

    en.wikipedia.org/wiki/Individually_ventilated_cage

    The cages are constructed and designed in a specific way to ensure an absolute microparticle free inner environment. This generally includes a cage bottom, a cage top (with a food hopper and water bottle holder incorporated) and a filter lid. It is also designed to allow maximum comfort of the animal and to provide a secure, chew proof environment.

  5. Management of heart failure - Wikipedia

    en.wikipedia.org/wiki/Management_of_heart_failure

    It remains unknown if surgery is superior to optimal medical therapy. The STICH trial (Surgical Treatment for IschemiC Heart Failure) will examine the role of medical treatment, coronary artery bypass surgery and left ventricle remodeling surgery in heart failure patients. Results are expected to be published in 2009 [needs update] and 2011. [56]

  6. Bruce protocol - Wikipedia

    en.wikipedia.org/wiki/Bruce_protocol

    The Modified Bruce protocol starts at a lower workload than the standard test and is typically used for elderly or sedentary patients. The first two stages of the Modified Bruce Test are performed at a 1.7 mph and 0% grade and 1.7 mph and 5% grade, and the third stage corresponds to the first stage of the Standard Bruce Test protocol as listed ...

  7. Operant conditioning chamber - Wikipedia

    en.wikipedia.org/wiki/Operant_conditioning_chamber

    Commonly used animals include rodents (usually lab rats), pigeons, and primates. The chamber is often sound-proof and light-proof to avoid distracting stimuli. Operant conditioning chambers have at least one response mechanism that can automatically detect the occurrence of a behavioral response or action (i.e., pecking , pressing, pushing, etc.).

  8. Laboratory rat - Wikipedia

    en.wikipedia.org/wiki/Laboratory_rat

    Laboratory rats or lab rats are strains of the rat subspecies Rattus norvegicus domestica (Domestic Norwegian rat) which are bred and kept for scientific research. While less commonly used for research than laboratory mice , rats have served as an important animal model for research in psychology and biomedical science [ 1 ] , and "lab rat" is ...

  9. Behavioral sink - Wikipedia

    en.wikipedia.org/wiki/Behavioral_sink

    Individual rats would rarely eat except in the company of other rats. As a result extreme population densities developed in the pen adopted for eating, leaving the others with sparse populations. In the experiments in which the behavioral sink developed, infant mortality ran as high as 96 percent among the most disoriented groups in the population.

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