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Other circumstances also affect the body's temperature. The core body temperature of an individual tends to have the lowest value in the second half of the sleep cycle; the lowest point, called the nadir, is one of the primary markers for circadian rhythms. The body temperature also changes when a person is hungry, sleepy, sick, or cold.
Immunisation against infectious disease, popularly known as The Green Book, provides information on vaccines for vaccine-preventable diseases. It acts as a guide to the UK's vaccination schedule for health professionals and health departments that give vaccines in the United Kingdom. The first two editions were published in 1992 and 1996.
The committee was established in 1963, having been until then an advisory board for polio immunisation. [1] It gained statutory status as the Standing Advisory Committee on Vaccination and Immunisation, a non-departmental public body [2] advising the Secretary of State for Social Services and the Secretary of State for Wales, under the National Health Service (Standing Advisory Committees ...
Skin temperature is the temperature of the outermost surface of the body. Normal human skin temperature on the trunk of the body varies between 33.5 and 36.9 °C (92.3 and 98.4 °F), though the skin's temperature is lower over protruding parts, like the nose, and higher over muscles and active organs. [ 1 ]
Aural and skin temperature measurements require special devices designed to measure temperature from these locations. [11] While 37 °C (99 °F) is considered "normal" body temperature, there is some variance between individuals. Most have a normal body temperature set point that falls within the range of 36.0 to 37.5 °C (96.8 to 99.5 °F). [13]
By the end of October 2008, this had risen to over 10M bookings, with daily figures of over 20,000. All primary care trusts in England were live with Choose and Book (although that might only be one GP within a PCT or practice), while all NHS acute trusts and a large number of independent sector hospitals used Choose and Book. At 28 October ...
On 2 December 2020, the UK became the first country to give approval for use of the Pfizer–BioNTech vaccine, [36] [37] later branded as Comirnaty. [38] This was in the form of a temporary authorisation given by the Medicines and Healthcare products Regulatory Agency (MHRA) under Regulation 174 of the Human Medicines Regulations 2012. [39]
A US soldier holding the Pfizer–BioNTech vaccine. Pfizer and BioNTech are manufacturing the vaccine in their own facilities in the United States and in Europe. The license to distribute and manufacture the vaccine in China was purchased by Fosun, alongside its investment in BioNTech. [47] [137] Manufacturing the vaccine requires a three-stage ...