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RNA folding problem: Is it possible to accurately predict the secondary, tertiary and quaternary structure of a polyribonucleic acid sequence based on its sequence and environment? Protein design : Is it possible to design highly active enzymes de novo for any desired reaction?
Experiments might be categorized according to a number of dimensions, depending upon professional norms and standards in different fields of study. In some disciplines (e.g., psychology or political science), a 'true experiment' is a method of social research in which there are two kinds of variables.
The history of scientific method considers changes in the methodology of scientific inquiry, not the history of science itself. The development of rules for scientific reasoning has not been straightforward; scientific method has been the subject of intense and recurring debate throughout the history of science, and eminent natural philosophers and scientists have argued for the primacy of ...
Experimental biology is the set of approaches in the field of biology concerned with the conduction of experiments to investigate and understand biological phenomena. The term is opposed to theoretical biology which is concerned with the mathematical modelling and abstractions of the biological systems.
Experiment that has two or more groups of subjects each being tested by a different testing factor simultaneously Student's t-test , Analysis of variance , Mann–Whitney U test Repeated measures design
The use of a sequence of experiments, where the design of each may depend on the results of previous experiments, including the possible decision to stop experimenting, is within the scope of sequential analysis, a field that was pioneered [12] by Abraham Wald in the context of sequential tests of statistical hypotheses. [13]
Reproducibility, closely related to replicability and repeatability, is a major principle underpinning the scientific method.For the findings of a study to be reproducible means that results obtained by an experiment or an observational study or in a statistical analysis of a data set should be achieved again with a high degree of reliability when the study is replicated.
Replication is one of the central issues in any empirical science. To confirm results or hypotheses by a repetition procedure is at the basis of any scientific conception. A replication experiment to demonstrate that the same findings can be obtained in any other place by any other researcher is conceived as an operationalization of objectivity.