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Dose adjustment is required in the elderly and in those with renal impairment. [3] Ciprofloxacin is weakly bound to serum proteins (20–40%). It is an inhibitor of the drug-metabolizing enzyme cytochrome P450 1A2, which leads to the potential for clinically important drug interactions with drugs metabolized by that enzyme. [5]
Ciprofloxacin, a fluoroquinolone antibiotic, has shown in vitro activity against many Gram-positive and Gram-negative bacteria including Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Pseudomonas aeruginosa.
Eye, ear or bladder infections; usually applied directly to the eye or inhaled into the lungs; rarely given by injection, although the use of intravenous colistin is experiencing a resurgence due to the emergence of multi drug resistant organisms. Kidney and nerve damage (when given by injection)
Quinolone antibiotics constitute a large group of broad-spectrum bacteriocidals that share a bicyclic core structure related to the substance 4-quinolone. [1] They are used in human and veterinary medicine to treat bacterial infections, as well as in animal husbandry, specifically poultry production.
Extremely advanced TB: 40 to 60 mg daily tapered off over 4 to 8 weeks TB in children: 2 to 5 mg/kg/day for one week, 1 mg/kg/day the next week, then tapered off over 5 weeks Steroids may be of benefit in peritonitis , miliary disease , tubercular osteomyelitis, TB osteomyelitis, laryngeal TB, lymphadenitis, and genitourinary disease, but the ...
Ciprofloxacin/celecoxib or PrimeC is a fixed-dose combination of ciprofloxacin and celecoxib developed for ALS. [1] [2] References
Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.The intravenous route of administration is commonly used for rehydration or to provide nutrients for those who cannot, or will not—due to reduced mental states or otherwise—consume food or water by mouth.
50 mg 20% 4 Anileridine [16] 1 ⁄ 4: 40 mg Alphaprodine: 1 ⁄ 6: 40–60 mg Tapentadol [17] 3 ⁄ 10: 32 mg 32% (fasting) Pethidine (meperidine) 1 ⁄ 3: 30 mg SC/IV/IM. 300 mg 50–60% Orally, 100% SC/IV/IM: 3–5 5–15 sec if IV, 15–25 min if orally Dipipanone [18] [19] 2 ⁄ 5: 25 mg 3.2–3.8 hours ±4 hours Benzylfentanyl: 1 ⁄ 2: AH ...