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Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum that dismantles collagen.It is used as a powder-and-solvent injection kit for the treatment of Dupuytren's contracture, a condition where the fingers bend towards the palm and cannot be fully straightened, and Peyronie's disease, a connective tissue disorder involving the growth of fibrous ...
Auxilium Pharmaceuticals , a $910 million biopharmaceutical company, announced today it is expanding a license agreement with BioSpecifics Technologies giving Auxilium the right to market Xiaflex ...
Dupuytren's contracture (also called Dupuytren's disease, Morbus Dupuytren, Palmar fibromatosis and historically as Viking disease or Celtic hand) is a condition in which one or more fingers become permanently bent in a flexed position. [2]
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This expanded Endo's portfolio to include 12 additional products, including a variery of testosterone preparations, and Xiaflex (a treatment for Peyronie's disease) [30] [31] In the same year they also acquired Dava Pharmaceuticals. [32] [33] 2015: Endo acquired the specialty generics and sterile injectables company Par Pharmaceutical for $8.05 ...
Spain's banks get up to a $125 billion bailout and China cut its interest rates, but persistent worries over global growth haven't been enough to break down the wall of optimism holding stocks up.
This group of metallopeptidases constitutes the MEROPS peptidase family M9, subfamilies M9A and M9B (microbial collagenase, clan MA(E)). The protein fold of the peptidase domain for members of this family resembles that of thermolysin, the type example for clan MA and the predicted active site residues for members of this family and thermolysin occur in the motif HEXXH.