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This template is intended for use on nucleic acid structure pages. To insert use: {{DNA RNA structure}}. On the primary, secondary, tertiary and quaternary structure pages, it displays alternative versions of the image with the relevant section highlighted. Alternatively, for the non-interactive image, use [[File:DNA RNA structure (full).png]]
This template is intended for use on nucleic acid structure pages. To insert use: {{DNA RNA structure}}. On the primary, secondary, tertiary and quaternary structure pages, it displays alternative versions of the image with the relevant section highlighted. Alternatively, for the non-interactive image, use [[File:DNA RNA structure (full).png]]
Ribonucleic acid (RNA) is a polymeric molecule that is essential for most biological functions, either by performing the function itself (non-coding RNA) or by forming a template for the production of proteins (messenger RNA). RNA and deoxyribonucleic acid (DNA) are nucleic acids.
A highly evolved [vague] RNA polymerase ribozyme was able to function as a reverse transcriptase, that is, it can synthesize a DNA copy using an RNA template. [36] Such an activity is considered [by whom?] to have been crucial for the transition from RNA to DNA genomes during the early history of life on earth. Reverse transcription capability ...
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Antisense oligonucleotides can be used to target a specific, complementary (coding or non-coding) RNA. If binding takes place this hybrid can be degraded by the enzyme RNase H. [12] RNase H is an enzyme that hydrolyzes RNA, and when used in an antisense oligonucleotide application results in 80-95% down-regulation of mRNA expression. [6]
Although RNA can also be amplified by PCR using a reverse transcriptase (in order to synthesize a complementary DNA strand as a template), NASBA's main advantage is that it works under isothermal conditions – usually at a constant temperature of 41 °C or two different temperatures, depending on the primers and enzymes used. Even when two ...
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