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[5] [19] The Essential Medicines List (EML) was updated in July 2023 to its 23rd edition. This list contains 1200 recommendations for 591 drugs and 103 therapeutic equivalents. [20] A separate list for children up to 12 years of age, known as the WHO Model List of Essential Medicines for Children (EMLc), was created in 2007 and is in its 9th ...
Andexanet alfa is a biologic agent, a recombinant modified version of human activated factor X (FXa). [17] Andexanet alfa differs from native FXa due to the removal of a 34 residue fragment that contains the Gla domain. This modification reduces andexanet alfa's anticoagulant potential. Additionally, a serine to alanine (S419A) mutation in the ...
Disease-modifying antirheumatic drugs (DMARDs) comprise a category of otherwise unrelated disease-modifying drugs defined by their use in rheumatoid arthritis to slow down disease progression. [1][2] The term is often used in contrast to nonsteroidal anti-inflammatory drugs (which refers to agents that treat the inflammation, but not the ...
Ro15-4513 (IUPAC: Ethyl-8-azido-5,6-dihydro-5-methyl-6-oxo-4H-imidazo-1,4-benzodiazepine-3-carboxylate)[1] is a weak partial inverse agonist of the benzodiazepine class of drugs, developed by Hoffmann–La Roche in the 1980s. [2] It acts as an inverse agonist (which acts in a similar way as a competitive antagonist), and can therefore be an ...
An antidote is a substance that can counteract a form of poisoning. [ 1 ] The term ultimately derives from the Greek term φάρμακον ἀντίδοτον (pharmakon antidoton), " (medicine) given as a remedy". Antidotes for anticoagulants are sometimes referred to as reversal agents. [ 2 ]
Ciprofloxacin is a broad-spectrum antibiotic of the fluoroquinolone class. It is active against some Gram-positive and many Gram-negative bacteria. [79] It functions by inhibiting a type II topoisomerase (DNA gyrase) and topoisomerase IV, [80][81] necessary to separate bacterial DNA, thereby inhibiting cell division.
The patch is labelled with the time and date of administration as well as the administrator's initials. Microneedle patch size comparison [ 1 ] A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream.
Template:Drugs for functional gastrointestinal disorders. Template:Drugs for obstructive airway diseases. Template:Drugs for peptic ulcer and GORD. Template:Drugs for treatment of bone diseases. Template:Drugs for treatment of hyperkalemia and hyperphosphatemia. Template:Drugs used in benign prostatic hypertrophy.
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