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  2. Water-reactive substances - Wikipedia

    en.wikipedia.org/wiki/Water-reactive_substances

    Water-reactive substances [1] are those that spontaneously undergo a chemical reaction with water, often noted as generating flammable gas. [2] Some are highly reducing in nature. [ 3 ] Notable examples include alkali metals , lithium through caesium , and alkaline earth metals , magnesium through barium .

  3. Organolithium reagent - Wikipedia

    en.wikipedia.org/wiki/Organolithium_reagent

    Sample aldol reaction with lithium enolate. Lithium enolate formation can be generalized as an acid–base reaction, in which the relatively acidic proton α to the carbonyl group (pK =20-28 in DMSO) reacts with organolithium base. Generally, strong, non-nucleophilic bases, especially lithium amides such LDA, LiHMDS and LiTMP are used.

  4. n-Butyllithium - Wikipedia

    en.wikipedia.org/wiki/N-Butyllithium

    This lithium–halogen exchange reaction is useful for preparation of several types of RLi compounds, particularly aryllithium and some vinyllithium reagents. The utility of this method is significantly limited, however, by the presence in the reaction mixture of n -BuBr or n -BuI, which can react with the RLi reagent formed, and by competing ...

  5. Reactivity series - Wikipedia

    en.wikipedia.org/wiki/Reactivity_series

    Even with this proviso, the electrode potentials of lithium and sodium – and hence their positions in the electrochemical series – appear anomalous. The order of reactivity, as shown by the vigour of the reaction with water or the speed at which the metal surface tarnishes in air, appears to be Cs > K > Na > Li > alkaline earth metals,

  6. Gilman reagent - Wikipedia

    en.wikipedia.org/wiki/Gilman_reagent

    Lithium dimethylcopper (CH 3) 2 CuLi can be prepared by adding copper(I) iodide to methyllithium in tetrahydrofuran at −78 °C. In the reaction depicted below, [ 4 ] the Gilman reagent is a methylating reagent reacting with an alkyne in a conjugate addition , and the ester group forms a cyclic enone .

  7. Corey–House synthesis - Wikipedia

    en.wikipedia.org/wiki/Corey–House_synthesis

    The Corey–House synthesis (also called the Corey–Posner–Whitesides–House reaction and other permutations) is an organic reaction that involves the reaction of a lithium diorganylcuprate with an organic halide or pseudohalide (′) to form a new alkane, as well as an ill-defined organocopper species and lithium (pseudo)halide as byproducts.

  8. Lithium amide - Wikipedia

    en.wikipedia.org/wiki/Lithium_amide

    Lithium amide or lithium azanide is an inorganic compound with the chemical formula LiNH 2. It is a white solid with a tetragonal crystal structure. [1] Lithium amide can be made by treating lithium metal with liquid ammonia: [2] 2 Li + 2 NH 3 → 2 LiNH 2 + H 2. Lithium amide decomposes into ammonia and lithium imide upon heating. [3]

  9. Lithium sulfate - Wikipedia

    en.wikipedia.org/wiki/Lithium_sulfate

    Lithium ion (Li +) is used in psychiatry for the treatment of mania, endogenous depression, and psychosis, and also for treatment of schizophrenia. Usually lithium carbonate (Li 2 CO 3) is applied, but sometimes lithium citrate (Li 3 C 6 H 5 O 7), lithium sulfate or lithium oxy-butyrate are used as alternatives. [12] Li + is not metabolized.