Search results
Results from the WOW.Com Content Network
Vincristine, also known as leurocristine and marketed under the brand name Oncovin among others, is a chemotherapy medication used to treat a number of types of cancer. [5] This includes acute lymphocytic leukemia , acute myeloid leukemia , Hodgkin's disease , neuroblastoma , and small cell lung cancer among others. [ 5 ]
Vinorelbine has a number of side-effects that can limit its use: Chemotherapy-induced peripheral neuropathy (a progressive, enduring and often irreversible tingling numbness, intense pain, and hypersensitivity to cold, beginning in the hands and feet and sometimes involving the arms and legs [11]), lowered resistance to infection, bruising or bleeding, anaemia, constipation, vomitings ...
Vinblastine is a vinca alkaloid [9] [2] [10] and a chemical analogue of vincristine. [11] [12] It binds tubulin, thereby inhibiting the assembly of microtubules. [13]Vinblastine treatment causes M phase specific cell cycle arrest by disrupting microtubule assembly and proper formation of the mitotic spindle and the kinetochore, each of which are necessary for the separation of chromosomes ...
These compounds include vinblastine, vincristine, vindesine, and vinorelbine. Additional researched vinca alkaloids include vincaminol, vineridine, and vinburnine. Vinpocetine is a semi-synthetic derivative of vincamine (sometimes described as "a synthetic ethyl ester of apovincamine"). [14]
The dimerization of catharanthine and vindoline produces the anti-cancer drugs vinblastine and vincristine. [10] The natural concentrations of catharanthine and vindoline are much higher than the concentrations of vinblastine and vincristine, which suggests that the reaction between catharanthine and vindoline is a rate-limiting step in the two ...
For premium support please call: 800-290-4726 more ways to reach us
The WHO balances the low risk of transmission through breast feeding from women who are on ART with the benefits of breastfeeding against diarrhea, pneumonia and malnutrition. It also strongly recommends that breastfeeding infants receive prophylactic ART. [44] In the US, the DHHS recommends against women with HIV breastfeeding. [67]
In chemotherapy as a conditioning regimen in hematopoietic stem cell transplantation, a study of people conditioned with cyclophosphamide alone for severe aplastic anemia came to the result that ovarian recovery occurred in all women younger than 26 years at time of transplantation, but only in five of 16 women older than 26 years.