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The SOLiD Sequencing System uses probes with dual base encoding. The underlying chemistry is summarized in the following steps: [12] - Step 1, Preparing a Library: This step begins with shearing the genomic DNA into small fragments. Then, two different adapters are added (for example A1 and A2).
A mnemonic is a memory aid used to improve long-term memory and make the process of consolidation easier. Many chemistry aspects, rules, names of compounds, sequences of elements, their reactivity, etc., can be easily and efficiently memorized with the help of mnemonics.
Due to the two base encoding system, an inherent accuracy check is built into the technology and offers 99.94% accuracy. The chemistry of the systems also means that it is not hindered by homopolymers unlike the Roche 454 FLX system and so large and difficult homopolymer repeat regions are no longer a problem to sequence.
Chen–Ho encoding is a memory-efficient alternate system of binary encoding for decimal digits.. The traditional system of binary encoding for decimal digits, known as binary-coded decimal (BCD), uses four bits to encode each digit, resulting in significant wastage of binary data bandwidth (since four bits can store 16 states and are being used to store only 10), [1] even when using packed BCD.
[1] [2] The standard genetic code is traditionally represented as an RNA codon table, because when proteins are made in a cell by ribosomes, it is messenger RNA (mRNA) that directs protein synthesis. [2] [3] The mRNA sequence is determined by the sequence of genomic DNA. [4] In this context, the standard genetic code is referred to as ...
DNA encoded chemical libraries (DECLs) are synthesized by the combinatorial chemistry principle and it clearly agrees with their application. [5] Fig. 1 DNA-encoded library displaying chemical compounds Schematic representation of DNA-encoded library displaying chemical compounds directly attached to oligonucleotides. a) Library generated by ...
E–Z configuration, or the E–Z convention, is the IUPAC preferred method of describing the absolute stereochemistry of double bonds in organic chemistry.It is an extension of cis–trans isomer notation (which only describes relative stereochemistry) that can be used to describe double bonds having two, three or four substituents.
A binary-to-text encoding is encoding of data in plain text. More precisely, it is an encoding of binary data in a sequence of printable characters . These encodings are necessary for transmission of data when the communication channel does not allow binary data (such as email or NNTP ) or is not 8-bit clean .