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While rainbow diet pills were banned in the US in the late 1960s, they reappeared in South America and Europe in the 1980s. [38] In 1959, phentermine had been FDA approved and fenfluramine in 1973. In the early 1990s two studies found that a combination of the drugs was more effective than either on its own; fen-phen became popular in the ...
Vasculitis [3] Alpidem (Ananxyl) 1995. Worldwide. Not approved in the US, withdrawn in France in 1994 [4] and the rest of the market in 1995 because of rare but serious hepatotoxicity. [3][5] Alosetron (Lotronex) 2000. US. Serious gastrointestinal adverse events; ischemic colitis; severe constipation. [2]
Fenfluramine as a single drug was first introduced in the 1970s, but was not popular because it only temporarily reduced weight. [1] A 1984 study found a weight loss of 7.5 kg on average in 24 weeks, as compared to 4.4 kg under placebo. [4] It sold modestly until the 1990s, when it was combined with phentermine and heavily marketed.
The USAF banned the use of dextroamphetamine, [53] and due to amphetamines' addiction potential in some people, newer wakefulness-promoting drugs such as modafinil have been seen as possible safer alternatives for military use (as a go pill) in some countries, including the United States.
TrimSpa. TrimSpa was a dietary supplement designed for weight loss, marketed by the company Goen Technologies and headed by Alexander Szynalski. [1] The ephedra -based supplement was marketed by TrimSpa to help "stave off hunger", [2] until ephedra was banned from the United States. TrimSpa's parent company, Goen Technologies, filed for ...
Fenfluramine is a substituted amphetamine and is also known as 3-trifluoromethyl- N -ethylamphetamine. [8] It is a racemic mixture of two enantiomers, dexfenfluramine and levofenfluramine. [8] Some analogues of fenfluramine include norfenfluramine, benfluorex, flucetorex, and fludorex.
Metabolife International, Inc. was a multi-level marketing company based in San Diego, California which manufactured dietary supplements. Metabolife's best-selling product, an ephedra supplement called Metabolife 356, once generated hundreds of millions of dollars in annual sales. [ 1] However, Metabolife 356 and other ephedra-containing ...
Phentermine (phenyl-tertiary-butyl amine), sold under the brand name Ionamin among others, is a medication used together with diet and exercise to treat obesity. [3] It is taken by mouth for up to a few weeks at a time, after which the benefits subside. [3]
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