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Nitroglycerin, also known as glyceryl trinitrate (GTN), is a vasodilator used for heart failure, high blood pressure (hypertension), anal fissures, painful periods, and to treat and prevent chest pain caused by decreased blood flow to the heart or due to the recreational use of cocaine.
This drug provides an antidote effect more quickly than formation of methemoglobin, but a clear superiority to methemoglobin formation has not been demonstrated. Cobalt complexes are quite toxic, and there have been accidents reported in the UK where patients have been given dicobalt-EDTA by mistake based on a false diagnosis of cyanide poisoning.
Two distinct drug classes in which cardiotoxicity can occur are in anti-cancer and antiarrhythmic drugs. Anti-cancer drug classes that cause cardiotoxicity include anthracyclines, monoclonal antibodies, and antimetabolites. This form generally manifests as a progressive form of heart failure, but can also manifest as an harmful arrhythmia. [2]
Like most drugs, flakka comes with a comedown. This sensation often results in users returning to the drug to get rid of the negative feeling, jump-starting a cycle of use that can lead to abuse.
GLP-1 drugs like Ozempic and Wegovy may affect your sense of taste and the way your brain responds to sweet foods.
Some patients may experience the texture as a chalky liquid, similar to calcium carbonate containing liquid antacids and with a slight medicinal taste. [12] Some preparations of barium sulfate have added flavors to make them easier to tolerate. In general, the flavor is considered unpleasant, and is dependent on the exact makeup of the drink. [13]
Disulfiram does not reduce alcohol cravings, so a major problem associated with this drug is extremely poor compliance. Methods to improve compliance include subdermal implants, which release the drug continuously over a period of up to 12 weeks, and supervised administration practices, for example, having the drug regularly administered by one ...
Captopril, sold under the brand name Capoten among others, is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and some types of congestive heart failure. Captopril was the first oral ACE inhibitor found for the treatment of hypertension. [3] It does not cause fatigue as associated with beta-blockers.