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[3] [1] [4] [5] NV-5138 works by binding to and modulating sestrin2, a cellular sensor protein for the amino acid leucine, which is a natural activator of mammalian target of rapamycin complex 1 (mTORC1) signaling pathway.
NOBS is the main bleach activator used in the U.S.A. and Japan. [4] Compared to TAED, which is the predominant bleach activator used in Europe, NOBS is efficient at much lower temperatures. At 20 °C NOBS is 100 times more soluble than TAED in water. [5]
The class of Chromadorea also utilizes the enzyme phospholipase C to regulate the releases of calcium. The enzyme releases inositol 1,4,5-trisphosphate (IP3) that denotes a signaling pathway involved in activating ovulation, the propelling of the oocyte into the spermatheca. This gene is involved in various activities like controlling GTPase ...
A transcriptional activator is a protein (transcription factor) that increases transcription of a gene or set of genes. [1] Activators are considered to have positive control over gene expression, as they function to promote gene transcription and, in some cases, are required for the transcription of genes to occur.
Tetraacetylethylenediamine, commonly abbreviated as TAED, is an organic compound with the formula (CH 3 C(O)) 2 NCH 2 CH 2 N(C(O)CH 3) 2. This white solid is commonly used as a bleach activator in laundry detergents and for paper pulp. It is produced by acetylation of ethylenediamine.
The property of the GAL1-GAL10 to bind the GAL4 protein is utilised in the GAL4/UAS technique for controlled gene mis-expression in Drosophila. This is the most popular form of binary expression in Drosophila melanogaster, a system which has been adapted for many uses to make Drosophila melanogaster one of the most genetically tractable multicellular organisms. [5]
[2] [3] Binding of the activator-coactivator complex increases the speed of transcription by recruiting general transcription machinery to the promoter, therefore increasing gene expression. [3] [4] [5] The use of activators and coactivators allows for highly specific expression of certain genes depending on cell type and developmental stage. [2]
The tool's design is based on a dental impactor, [6] a device that taps dental amalgam into cavities in teeth. [4] Activator I was patented by Activator Methods International on September 26, 1978. [4] [7] [8] Activator II was released, with an added "impedance head", in 1994. [4]