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  2. Telmisartan - Wikipedia

    en.wikipedia.org/wiki/Telmisartan

    Serious side effects may include kidney problems, low blood pressure, and angioedema. [6] Use in pregnancy may harm the baby and use when breastfeeding is not recommended. [1] It is an angiotensin II receptor antagonist and works by blocking the effects of angiotensin II. [6] Telmisartan was patented in 1991 and came into medical use in 1999. [7]

  3. Telmisartan/hydrochlorothiazide - Wikipedia

    en.wikipedia.org/wiki/Telmisartan/...

    It may be used if telmisartan by itself is not sufficient. [5] It is taken by mouth. [5] Common side effects include dizziness, upper respiratory tract infections, nausea, diarrhea, and tiredness. [2] Severe side effects may include kidney problems, electrolyte problems, and allergic reactions. [2] Use during pregnancy may harm the baby. [2]

  4. Telmisartan/amlodipine - Wikipedia

    en.wikipedia.org/wiki/Telmisartan/amlodipine

    It is a combination of telmisartan, an angiotensin II receptor antagonist, and amlodipine, as the besilate, a calcium channel blocker. [2] It is taken by mouth. [2] Common side effects include dizziness, swelling, and back pain. [2] Severe side effects may include low blood pressure, kidney problems, electrolyte problems, and a heart attack. [2]

  5. Angiotensin II receptor blocker - Wikipedia

    en.wikipedia.org/wiki/Angiotensin_II_receptor...

    The rates as listed in the U.S. Food and Drug Administration (FDA) Package Inserts (PIs) for inhibition of this effect at the 24th hour for the ARBs are as follows: Valsartan – 30% at 80 mg; Telmisartan – 40% at 80 mg; Losartan – 25–40% at 100 mg; Irbesartan – 40% at 150 mg; 60% 300 mg; Azilsartan – 60% at 32 mg

  6. WHO Model List of Essential Medicines for Children - Wikipedia

    en.wikipedia.org/wiki/WHO_Model_List_of...

    The selection and use of essential medicines: report of the WHO Expert Committee, 2017 (including the 20th WHO Model List of Essential Medicines and the 6th Model List of Essential Medicines for Children). Geneva: World Health Organization. hdl: 10665/259481. ISBN 978-92-4-121015-7. ISSN 0512-3054. WHO technical report series; no. 1006.

  7. Preterm birth - Wikipedia

    en.wikipedia.org/wiki/Preterm_birth

    Tobacco is the most commonly used drug during pregnancy and contributes significantly to low birth weight delivery. [62] Babies with birth defects are at higher risk of being born preterm. [63] Passive smoking and/or smoking before the pregnancy influences the probability of a preterm birth.

  8. Drug titration - Wikipedia

    en.wikipedia.org/wiki/Drug_titration

    Drug titration is the process of adjusting the dose of a medication for the maximum benefit without adverse effects. [ 1 ] When a drug has a narrow therapeutic index , titration is especially important, because the range between the dose at which a drug is effective and the dose at which side effects occur is small. [ 2 ]

  9. Discovery and development of angiotensin receptor blockers

    en.wikipedia.org/wiki/Discovery_and_development...

    The first one is the imidazole ring that binds to amino acids in helix 7 (Asn 295). The second group is the biphenyl-methyl group that binds to amino acids in both helices 6 and 7 (Phe 301, Phe 300, Trp 253 and His 256). The third one is the tetrazole group that interacts with amino acids in helices 4 and 5 (Arg 167 and Lys 199).

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