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Down syndrome is the most common chromosomal abnormality, [25] occurring in about 1 in 1,000 babies born worldwide, [1] and one in 700 in the US. [17] In 2015, there were 5.4 million people with Down syndrome globally, of whom 27,000 died, down from 43,000 deaths in 1990.
This is a list of people with Down syndrome, a condition also known as Down's syndrome or trisomy 21. Down syndrome is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. [1] It is typically associated with developmental delays, characteristic physical features, and mild to moderate intellectual disability ...
Down used this reasoning to argue against a tendency he perceived in his day to regard different races as separate species. Down was an advocate for higher education for women and disagreed with the notion that it would make the women liable to produce "feeble-minded" children. [9] He also believed women should be allowed to join the workforce.
Pablo Pineda (born 5 August 1974) is a Spanish actor who received the Concha de Plata Award at the 2009 San Sebastián International Film Festival for his performance in the film Yo, también. [1] In the film, he plays the role of a university graduate with Down syndrome , which is quite similar to his real life.
An anaphase lag of a chromosome 21 in a Down syndrome embryo leads to a fraction of euploid cells (2n cells), phenomenon described as "aneuploidy rescue". There is considerable variability in the fraction of cells with trisomy 21, both as a whole and tissue-by-tissue. This is the cause of 1–2% of the observed Down syndromes. [4]
A World Down Syndrome Day celebration in Brazil. World Down Syndrome Day (WDSD) is marked each year on March 21, [1] beginning in 2007. The 21st day of March (the 3rd month of the year) was selected to signify the uniqueness of the triplication of the 21st chromosome which causes Down syndrome.
The song "Que nadie sepa mi sufrir", was composed in 1936 by Ángel Cabral, with (Spanish) lyrics by Enrique Dizeo, both of Argentine origin, as a Peruvian waltz.Peruvian waltz, also known as vals criollo ("creole waltz"), was a popular genre in Hispanic America between the 1930s and 1950s, and the song, initially covered by Argentine singer Hugo del Carril, became a regional hit.
Additionally, the second album of the renowned Chilean series 31 Minutos is titled 31 canciones de amor y una canción de Guaripolo ("31 Love Songs and a Guaripolo Song"), making reference to the title of Neruda's book. Twenty Love Poems and a Song of Despair remains Neruda's most well-known work and has sold millions of copies worldwide. [3]