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Together, these relationship were termed the "size principle". Decades of research elaborated on these initial finding on motor neuron properties and recruitment of motor units (neuron + muscle fibers), [7] and the relationship between neuron excitability and its size became a central focus of neurophysiology. [8]
Summation, which includes both spatial summation and temporal summation, is the process that determines whether or not an action potential will be generated by the combined effects of excitatory and inhibitory signals, both from multiple simultaneous inputs (spatial summation), and from repeated inputs (temporal summation).
Signal transmission from nerve to muscle at the motor end plate. The neuromuscular junction is the synapse that is formed between an alpha motor neuron (α-MN) and the skeletal muscle fiber. In order for a muscle to contract, an action potential is first propagated down a nerve until it reaches the axon terminal of the motor neuron.
The compound muscle action potential (CMAP) or compound motor action potential is an electrodiagnostic medicine investigation (electrical study of muscle function). The CMAP idealizes the summation of a group of almost simultaneous action potentials from several muscle fibers in the same area.
The summation of these three EPSPs generates an action potential. In neuroscience , an excitatory postsynaptic potential ( EPSP ) is a postsynaptic potential that makes the postsynaptic neuron more likely to fire an action potential .
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