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Nephrogenic systemic fibrosis is a rare syndrome that involves fibrosis of the skin, joints, eyes, and internal organs. NSF is caused by exposure to gadolinium in gadolinium-based MRI contrast agents (GBCAs) in patients with impaired kidney function. [1][2] Epidemiological studies suggest that the incidence of NSF is unrelated to gender or ...
The glomerular filtration rate is the flow rate of filtered fluid through the kidney. The creatinine clearance rate (C Cr or CrCl) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR. Creatinine clearance exceeds GFR due to creatinine secretion, [1] which can be blocked by ...
Gadolinium (III) containing MRI contrast agents (often termed simply "gado" or "gad") are the most commonly used for enhancement of vessels in MR angiography or for brain tumor enhancement associated with the degradation of the blood–brain barrier (BBB). [3][4] Over 450 million doses have been administered worldwide from 1988 to 2017. [5]
The Glomerular filtration rate (GFR) is regarded as the best overall measure of the kidney's ability to carry out these numerous functions. An estimate of the GFR is used clinically to determine the degree of kidney impairment and to track the progression of the disease. The GFR, however, does not reveal the source of the kidney disease.
Cardiac magnetic resonance imaging (cardiac MRI, CMR), also known as cardiovascular MRI, is a magnetic resonance imaging (MRI) technology used for non-invasive assessment of the function and structure of the cardiovascular system. [2] Conditions in which it is performed include congenital heart disease, cardiomyopathies and valvular heart ...
Gadoteric acid, sold under the brand name Dotarem among others, is a macrocycle -structured gadolinium-based MRI contrast agent (GBCA). It consists of the organic acid DOTA as a chelating agent, and gadolinium (Gd 3+), and is used in form of the meglumine salt (gadoterate meglumine). [4][5] The paramagnetic property of gadoteric acid reduces ...
The Panel’s 10 recommendations for cancer prevention are: Body Fatness: Be as lean as possible within the normal range of body weight. Physical Activity: Be physically active as part of everyday life. Regular activity and movement has been reported to keep hormone levels healthy. Some hormones when at a high level can increase your cancer risk.
A Montana cancer doctor for years saw up to 70 patients a day, double-billed federal health care programs and overprescribed pain medications to boost his income, the U.S. Attorney's Office said ...