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Phenylglycine is the organic compound with the formula C 6 H 5 CH(NH 2)CO 2 H. It is a non-proteinogenic alpha amino acid related to alanine, but with a phenyl group in place of the methyl group. It is a white solid. The compound exhibits some biological activity. [1]
Graupner M, White RH (2001). "The first examples of (S)-2-hydroxyacid dehydrogenases catalyzing the transfer of the pro-4S hydrogen of NADH are found in the archaea".
A. Acefylline; Aceglutamide; Acetylcysteine; Acetylleucine; Acetyllysine; O-Acetylserine; Acivicin; S-Adenosyl methionine; S-Adenosyl-L-homocysteine; Agaritine; Alanine
Biosynthesis of HPG. HPG is synthesized from prephenate, an intermediate in the shikimic acid pathway and also a precursor to tyrosine.Prephenate is aromatized by prephenate dehydrogenase (Pdh) using NAD + as a cofactor to produce 4-hydroxyphenylpyruvate. 4-Hydroxyphenylpyruvate is then oxidized by 4-hydroxymandelate synthase (4HmaS) using oxygen to form 4-hydroxymandelate and hydrogen ...
(RS)-MCPG is a phenylglycine derivative and a non-selective antagonist of group I and II metabotropic glutamate receptors (mGluRs). It has been used in long-term potentiation (LTP) as well as long-term depression (LTD) research and proved that certain LTP and LTD pathways depend on mGluRs.
Models are important in helping us understand the basic biology of the disease, but we need human studies in representative populations for ideas to be fully validated. Therefore, while these are ...
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(S)-3,5-Dihydroxyphenylglycine or DHPG is a potent agonist of group I metabotropic glutamate receptors (mGluRs) mGluR1 and mGluR5.. DHPG was the first agonist shown to be selective for group I mGluRs. [1]
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