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A trough level is contrasted with a "peak level" (C max), which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It is widely used in clinical trials for newer medicines to investigate therapeutic effectiveness and safety.
A trough is an elongated area of lower air pressure. Since pressure is closely linked to wind, there are often changes in wind direction across a trough. If a trough forms in the mid-latitudes, a temperature difference at some distance between the two sides of the trough usually exists and the trough might become a weather front at some
Trough (geology), a long depression less steep than a trench; Trough (meteorology), an elongated region of low atmospheric pressure; Trough (physics), the lowest point on a wave; Trough level (medicine), the lowest concentration of a medicine is present in the body over time; Langmuir-Blodgett trough, a laboratory instrument
Peak-to-trough ratio in pharmacokinetics is the ratio of peak (C max) and trough (C min) levels of a drug over its dosing interval (τ) at steady state.. Peak-to-trough ratio (PTR), also known as peak-to-trough variation or peak-to-trough fluctuation, is a parameter in pharmacokinetics which is defined as the ratio of C max (peak) concentration and C min (trough) concentration over a dosing ...
Shortwave trough with associated vorticity. A shortwave or shortwave trough is an embedded kink in the trough / ridge pattern. Its length scale is much smaller than that of and is embedded within longwaves, which are responsible for the largest scale (synoptic scale) weather systems.
Ridge line extending to the left of the high pressure center (H).In meteorology a ridge or barometric ridge is an elongated area of relatively high atmospheric pressure compared to the surrounding environment, without being a closed circulation. [1]
A tropical upper tropospheric trough (TUTT), also known as the mid-oceanic trough, [1] is a trough situated in the upper-level (at about 200 hPa) tropics. Its formation is usually caused by the intrusion of energy and wind from the mid-latitudes into the tropics. It can also develop from the inverted trough adjacent to an upper level anticyclone.
A trough is the opposite of a crest, so the minimum or lowest point of the wave. When the crests and troughs of two sine waves of equal amplitude and frequency intersect or collide, while being in phase with each other, the result is called constructive interference and the magnitudes double (above and below the line).