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2. Vitamin B12 - Wikipedia

   en.wikipedia.org/wiki/Vitamin_B12

   Vitamin B 12 is absorbed by a B 12-specific transport proteins or via passive diffusion. [12] Transport-mediated absorption and tissue delivery is a complex process involving three transport proteins: haptocorrin (HC), intrinsic factor (IF) and transcobalamin II (TC2), and respective membrane receptor proteins. HC is present in saliva.

3. Intrinsic factor - Wikipedia

   en.wikipedia.org/wiki/Intrinsic_factor

   Because vitamin B 12 absorption is a multistep process that involves the stomach, pancreas and small intestine, and is mediated by two carriers: Haptocorrin and intrinsic factor, and because Haptocorrin (transcobalamin I) binds to vitamin B 12, and Vitamin B 12 is acid-sensitive, when vitamin B 12 binds to Haptocorrin it can safely pass through ...

4. Transcobalamin - Wikipedia

   en.wikipedia.org/wiki/Transcobalamin

   TC-2 binds cobalamin once it has been taken up by enterocytes of the terminal ileum and the "Intrinsic Factor-Vitamin B12" complex has been degraded. TC-2 is then involved with the transport of Vitamin B12 to the tissues, where it binds to its plasma membrane receptor (TC-2R), a heavily glycosylated protein with a monomeric molecular mass of 62 ...

5. The Top Signs You Have a Vitamin B12 Deficiency - AOL

   www.aol.com/top-sign-vitamin-b12-deficiency...

   One of the superpowers of vitamin B12 is that it is the only water-soluble vitamin that can be stored in the human body, Kitchens points out, and it can remain stored in the liver for several ...

6. Vitamin B12 deficiency - Wikipedia

   en.wikipedia.org/wiki/Vitamin_B12_deficiency

   B 12 deficiency caused by Helicobacter pylori was positively correlated with CagA positivity and gastric inflammatory activity, rather than gastric atrophy. [130] Medications: long-term use of certain medications can result in poor absorption of dietary vitamin B 12. [1] These include medications to treat heartburn, and metformin to treat diabetes.

7. How to recognize the signs and symptoms of vitamin B12 ... - AOL

   www.aol.com/news/recognize-signs-symptoms...

   Vitamin B12 deficiency causes symptoms like fatigue, poor memory, a swollen tongue, and canker sores. Skip to main content. 24/7 Help. For premium support please call: 800-290-4726 more ways to ...