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The ears are often cleaned before administering the medication, since pus and cellular debris lessen the activity of amikacin. [35] Amikacin is administered to the eye when prepared as an ophthalmic ointment or solution, or when injected subconjunctivally. [38] Amikacin in the eye can be accompanied by cephazolin. Despite its use there amikacin ...
Streptomycin was the first effective drug in the treatment of tuberculosis, though the role of aminoglycosides such as streptomycin and amikacin has been eclipsed (because of their toxicity and inconvenient route of administration) except for multiple-drug-resistant strains.
Ototoxicity-induced hearing loss typically impacts the high frequency range, affecting above 8000 Hz prior to impacting frequencies below. [8] There is not global consensus on measuring severity of ototoxicity-induced hearing loss as there are many criteria available to define and measure ototoxicity-induced hearing loss.
Eye, ear or bladder infections; usually applied directly to the eye or inhaled into the lungs; rarely given by injection, although the use of intravenous colistin is experiencing a resurgence due to the emergence of multi drug resistant organisms. Kidney and nerve damage (when given by injection)
This infection causes respiratory illness in birds, pigs, and humans, especially in immunocompromised people. In the later stages of AIDS, it can be very severe. It usually first presents as a persistent cough. It is typically treated with a series of three antibiotics for a period of at least six months.
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Kanamycin A, [2] often referred to simply as kanamycin, is an antibiotic used to treat severe bacterial infections and tuberculosis. [3] It is not a first line treatment. [3] It is used by mouth, injection into a vein, or injection into a muscle. [3]
Signs and symptoms of ototoxicity include tinnitus, hearing loss, dizziness and nausea and/or vomiting. [3] The diagnosis of medicine-induced ototoxicity is challenging as it usually shows only mild symptoms in early stages. Thus, prospective ototoxicity monitoring would be required when patients are using ototoxic medications. [1]
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