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The cells of the neurovascular unit also make up the blood–brain barrier (BBB), which plays an important role in maintaining the microenvironment of the brain. [11] In addition to regulating the exit and entrance of blood, the blood–brain barrier also filters toxins that may cause inflammation, injury, and disease. [12]
The blood–cerebrospinal fluid barrier (BCSFB) is a fluid–brain barrier that is composed of a pair of membranes that separate blood from CSF at the capillary level and CSF from brain tissue. [14] The blood–CSF boundary at the choroid plexus is a membrane composed of epithelial cells and tight junctions that link them. [ 14 ]
Cerebral blood flow (CBF) is the blood supply to the brain in a given period of time. [8] In an adult, CBF is typically 750 millilitres per minute or 15.8 ± 5.7% of the cardiac output. [9] This equates to an average perfusion of 50 to 54 millilitres of blood per 100 grams of brain tissue per minute. [10] [11] [12]
After formation of the tube, the brain forms into three sections; the hindbrain, the midbrain, and the forebrain. The types of neuroectoderm include: Neural crest. pigment cells in the skin; ganglia of the autonomic nervous system; dorsal root ganglia. facial cartilage; aorticopulmonary septum of the developing heart and lungs; ciliary body of ...
All epithelia is usually separated from underlying tissues by an extracellular fibrous basement membrane. The lining of the mouth, lung alveoli and kidney tubules are all made of epithelial tissue. The lining of the blood and lymphatic vessels are of a specialised form of epithelium called endothelium.
The tumor occurs in the tissue covering the brain and spinal cord. The symptoms of the tumor are dependent on its location, but most children experience seizures that cannot be controlled by medication. DNT is usually treated through invasive surgery and the patients are usually capable of recovering fully, with little to no long-term effects. [9]
These form the ventricular system of the brain: [8] The neural stem cells of the developing brain, principally radial glial cells, line the developing ventricular system in a transient zone called the ventricular zone. [9] The prosencephalon divides into the telencephalon, which forms the cortex of the developed brain, and the diencephalon.
The ependyma is made up of ependymal cells called ependymocytes, a type of glial cell. These cells line the ventricles in the brain and the central canal of the spinal cord, which become filled with cerebrospinal fluid. These are nervous tissue cells with simple columnar shape, much like that of some mucosal epithelial cells. [2]