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Pepsin is expressed as a zymogen called pepsinogen, whose primary structure has an additional 44 amino acids compared to the active enzyme. In the stomach, gastric chief cells release pepsinogen. This zymogen is activated by hydrochloric acid (HCl), which is released from parietal cells in the stomach lining.
The enzyme is first made in the inactive form, pepsinogen by chief cells in the lining of the stomach. [24] With an impulse from the vagus nerve, pepsinogen is secreted into the stomach, where it mixes with hydrochloric acid to form pepsin. [25] Once active, pepsin works to break down proteins in foods such as dairy, meat, and eggs. [24]
Chief cells are part of fundic gland polyps (here shown in high magnification). [11]In gastric tissue, a loss of parietal cells due to chronic inflammation has been shown to affect chief cell differentiation and can induce chief cells to transdifferentiate back into neck cells and can lead to the formation of mucus cell metaplasia known as spasmolytic polypeptide expressing metaplasia (SPEM ...
Reading the label. You can tell a lot from the design and color of food packaging. The color of a packet of M&Ms, for example, can tell you whether they’re peanut, regular, crispy or caramel ...
The gastrointestinal hormones (or gut hormones) constitute a group of hormones secreted by enteroendocrine cells in the stomach, pancreas, and small intestine that control various functions of the digestive organs.
Bloated food packaging doesn’t always mean the food inside is dangerous to eat, says Zhang. If you live in a high-altitude area, such as Denver, a food package may swell because the air pressure ...
The cast of "Saturday Night Live" also tackled the TikTok shutdown in last night's episode. During the Weekend Update segment, comedians Michael Longfellow and Michael Che addressed the situation ...
Digestion is the breakdown of large insoluble food compounds into small water-soluble components so that they can be absorbed into the blood plasma.In certain organisms, these smaller substances are absorbed through the small intestine into the blood stream.