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Dose fractionation effects are utilised in the treatment of cancer with radiation therapy. When the total dose of radiation is divided into several, smaller doses over a period of several days, there are fewer toxic effects on healthy cells. This maximizes the effect of radiation on cancer and minimizes the negative side effects. A typical ...
Moist desquamation is a common side effect of radiotherapy treatment, where approximately 36% of radiotherpay patients will present with symptoms of moist desquamation. [3] While modern megavoltage external beam radiotherapy have peak radiation doses below the skin, older orthvoltage systems have
Radiation therapy (RT) is in itself painless, but has iatrogenic side effect risks. Many low-dose palliative treatments (for example, radiation therapy to bony metastases) cause minimal or no side effects, although short-term pain flare-up can be experienced in the days following treatment due to oedema compressing nerves in the treated area ...
Alternative assumptions for the extrapolation of the cancer risk vs. radiation dose to low-dose levels, given a known risk at a high dose: supra-linearity (A), linear (B), linear-quadratic (C) and hormesis (D). The linear dose-response model suggests that any increase in dose, no matter how small, results in an incremental increase in risk.
A very low dose of a chemical agent may trigger from an organism the opposite response to a very high dose.. Radiation hormesis proposes that radiation exposure comparable to and just above the natural background level of radiation is not harmful but beneficial, while accepting that much higher levels of radiation are hazardous.
A specific thickness of bolus can be applied to the skin to alter the dose received at depth in the tissue and on the skin surface. A typical example of this is the application of a defined thickness of bolus to a chest wall for post-mastectomy chest wall treatment, to increase the skin dose.
When the dosage is equal to 1/A, S = 0.37 (or e^-1). For this reason, D0 is often called the mean lethal dose, the dose that creates one lethal event per target on average. Curved cell survival curves (cells exposed to low-LET radiation) show two distinct regions: low dose regions and high dose regions.
Doctor reviewing a radiation treatment plan. In radiotherapy, radiation treatment planning (RTP) is the process in which a team consisting of radiation oncologists, radiation therapist, medical physicists and medical dosimetrists plan the appropriate external beam radiotherapy or internal brachytherapy treatment technique for a patient with cancer.