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Pernicious anemia often presents slowly, and can cause harm insidiously and unnoticeably. Untreated, it can lead to neurological complications, and in serious cases, death. [19] The onset may be vague and slow and the condition can be confused with other conditions, and there may be few to many symptoms without anemia. [20]
Its deficiency can cause neurodevelopmental problems which can be partly reversible with early treatment. [27] Only a small subset of dementia cases have been found to be reversible with vitamin B 12 therapy. [28] Tinnitus may be associated with vitamin B 12 deficiency. [29] Vitamin B 12 deficiency may accompany certain eating disorders or ...
Antacid drugs that neutralize stomach acid and drugs that block acid production (such as proton-pump inhibitors) will inhibit the absorption of B 12 by preventing the release from food in the stomach. [124] Other causes of B12 malabsorption include intrinsic factor deficiency, pernicious anemia, bariatric surgery pancreatic insufficiency ...
Other ways to get extra B12. A prescription form of vitamin B12 can be given as an injection, notes the NIH—typically for people with deficiencies who also have problems absorbing vitamin B12 as ...
Symptoms “A B12 deficiency can cause physical and neurological symptoms, and research is also growing to support that it can also cause psychological issues as well,” says Shapiro.
Pernicious anaemia is a lifelong condition that affects nearly 5 in 100,000 people in the UK.
As a result, the stomach's secretion of essential substances such as hydrochloric acid, pepsin, and intrinsic factor is impaired, leading to digestive problems. The most common are pernicious anemia possibly leading to vitamin B 12 deficiency ; and malabsorption of iron, leading to iron deficiency anaemia . [ 2 ]
Over time, a deficiency of B12 can cause problems with balance, confusion, depression, poor memory and possibly dementia, and it can even cause permanent damage to the nervous system, Somers says.
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