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Adrenal fatigue or hypoadrenia is a pseudo-scientific term used by alternative medicine providers to suggest that the adrenal glands are exhausted and unable to produce adequate quantities of hormones, primarily cortisol, due to chronic stress or infections. [1]
It can be safe to take ashwagandha supplements daily at the dosage recommended by your doctor, the experts say. Research suggests ashwagandha is well-tolerated for up to three months, per the NIH.
Clinical manifestations of adrenocorticotropic hormone deficiency are similar to those of primary adrenal insufficiency, except for cutaneous hyperpigmentation and electrolyte disturbances. [2] Adrenocorticotropic hormone deficiency is characterized by nonspecific symptoms such as fatigue, anorexia, unintentional weight loss, and hypoglycemia.
Primary adrenal insufficiency predisposes to higher risk of death, mostly due to infection, cardiovascular disease, and adrenal crisis. [2] Delayed diagnosis can impair quality of life, and lack of treatment brings high mortality. [2] However, with proper diagnosis, monitoring, and treatment, people with adrenal insufficiency can live normally. [3]
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