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Diabetic retinopathy (also known as diabetic eye disease) is a medical condition in which damage occurs to the retina due to diabetes.It is a leading cause of blindness in developed countries and one of the lead causes of sight loss in the world, even though there are many new therapies and improved treatments for helping people live with diabetes.
Intraretinal microvascular abnormalities (IRMA) are abnormalities of the blood vessels that supply the retina of the eye, a sign of diabetic retinopathy. [1] IRMA can be difficult to distinguish from and is likely a precursor to retinal neovascularization. One way to distinguish IRMA from retinal neovascularization is to perform fluorescein ...
The American Academy of Ophthalmology practice guidelines recommend laser coagulation for people who have both mild to moderate nonproliferative diabetic retinopathy (NPDR) and clinically significant macular edema outside the fovea; treatment with anti-VEGF drugs is better than laser coagulation for clinically significant macular edema in the fovea. [1]
The most common cause found in adults is diabetic retinopathy. Abnormal blood vessels can form in the back of the eye of a person with diabetes. These new blood vessels are weaker and prone to breaking and causing hemorrhage. [2] Diabetic retinopathy accounts for 31.5–54% of all cases of vitreous hemorrhage in adults in the United States. [1]
Non-insulin-dependent diabetes mellitus NRR Neuro-retinal rim NS Nuclear sclerosis: NTG Normal tension glaucoma: PDR Proliferative diabetic retinopathy PDT Photodynamic therapy: PK Penetrating keratoplasy: POAG Primary open-angle glaucoma PPDR Preproliferative diabetic retinopathy PRA Pan-retinal ablation PRK Photorefractive keratectomy PRP
There is an association between the grade of retinopathy and mortality. In a classic study in 1939 Keith and colleagues [6] described the prognosis of people with differing severity of retinopathy. They showed 70% of those with grade 1 retinopathy were alive after 3 years whereas only 6% of those with grade 4 survived.
Treatment is based on the cause of the retinopathy and may include laser therapy to the retina. Laser photocoagulation therapy has been the standard treatment for many types of retinopathy. Evidence shows that laser therapy is generally safe and improves visual symptoms in sickle cell and diabetic retinopathy.
PVR is graded as Grade A, B, or C by the Silicone Oil Study and as Grade A, B, C, or D by the Retina Society Terminology Committee. [10] Grade A is characterized by the appearance of vitreous haze and RPE cells in the vitreous. Grade B is characterized by wrinkling of the edges of the retinal tear or the inner retinal surface.
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